发明申请
US20150191712A1 ISOPRENE SYNTHASE VARIANTS FOR IMPROVED MICROBIAL PRODUCTION OF ISOPRENE
审中-公开
用于改善微生物生产异烟肼的异丙肾上腺素变异体
- 专利标题： ISOPRENE SYNTHASE VARIANTS FOR IMPROVED MICROBIAL PRODUCTION OF ISOPRENE
- 专利标题（中）： 用于改善微生物生产异烟肼的异丙肾上腺素变异体
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申请号： US14543628申请日： 2014-11-17
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公开(公告)号： US20150191712A1公开(公告)日： 2015-07-09
- 发明人: Richard R. BOTT , Marguerite A. Cervin , James T. Kellis, JR. , Joseph C. Mcauliffe , Andrei Miasnikov , Caroline M. Peres , Christopher L. Rife , Derek H. Wells , Walter Weyler , Gregory M. Whited
- 申请人： Danisco US Inc. , The Goodyear Tire & Rubber Company
- 主分类号： C12N9/88
- IPC分类号： C12N9/88
摘要：
The present invention provides methods and compositions comprising at least one isoprene synthase enzyme with improved catalytic activity and/or solubility. In particular, the present invention provides variant plant isoprene synthases for increased isoprene production in microbial host cells. Biosynthetically produced isoprene of the present invention finds use in the manufacture of rubber and elastomers.
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