Invention Application
US20150086512A1 METHODS OF PRODUCING RPE CELLS AND COMPOSITIONS OF RPE CELLS
审中-公开
RPE细胞的生产方法和RPE细胞的组成
- Patent Title: METHODS OF PRODUCING RPE CELLS AND COMPOSITIONS OF RPE CELLS
- Patent Title (中): RPE细胞的生产方法和RPE细胞的组成
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Application No.: US14254833Application Date: 2014-04-16
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Publication No.: US20150086512A1Publication Date: 2015-03-26
- Inventor: Christopher Malcuit , Linda Lemieux , William Holmes , Pedro Huertas , Lucy Vilner
- Applicant: Advanced Cell Technology, Inc.
- Applicant Address: US MA Marlborough
- Assignee: Advanced Cell Technology, Inc.
- Current Assignee: Advanced Cell Technology, Inc.
- Current Assignee Address: US MA Marlborough
- Main IPC: C12N5/079
- IPC: C12N5/079 ; A61K35/30
Abstract:
The present invention provides improved methods for producing RPE cells from human embryonic stem cells or from other human pluripotent stem cells. The invention also relates to human retinal pigmented epithelial cells derived from human embryonic stem cells or other human multipotent or pluripotent stem cells. hRPE cells derived from embryonic stem cells are molecularly distinct from adult and fetal-derived RPE cells, and are also distinct from embryonic stem cells. The hRPE cells described herein are useful for treating retinal degenerative diseases.
Public/Granted literature
- US10077424B2 Methods of producing RPE cells and compositions of RPE cells Public/Granted day:2018-09-18
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