发明申请
US20140235567A1 5'-SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES
有权
5'-取代的核苷衍生物及其用于治疗病毒性疾病的方法
- 专利标题： 5'-SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES
- 专利标题（中）： 5'-取代的核苷衍生物及其用于治疗病毒性疾病的方法
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申请号： US14232540申请日： 2012-07-10
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公开(公告)号： US20140235567A1公开(公告)日： 2014-08-21
- 发明人: Vishal A. Verma , Ashok Arasappan , F. George Njoroge , Vinay Girijavallabhan , Stephane L. Bogen , Qun Dang , David B. Olsen
- 申请人： Vishal A. Verma , Ashok Arasappan , F. George Njoroge , Vinay Girijavallabhan , Stephane L. Bogen , Qun Dang , David B. Olsen
- 国际申请： PCT/US12/46035 WO 20120710
- 主分类号： C07H19/14
- IPC分类号： C07H19/14 ; A61K45/06 ; A61K31/7056 ; A61K31/7064
摘要：
The present invention relates to 5′-Substituted Nucleoside Derivatives of Formula (I): (I) and pharmaceutically acceptable salts thereof, wherein B, X, Y, Z, R1, R2, R3 and R3′ are as defined herein. The present invention also relates to compositions comprising at least one 5′-Substituted Nucleoside Derivative, and methods of using the 5′-Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.
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