发明申请
US20140234210A1 METAL BISPHOSPHONATE NANOPARTICLES FOR ANTI-CANCER THERAPY AND IMAGING AND FOR TREATING BONE DISORDERS
有权
用于抗癌治疗和成像和治疗骨质疏松症的金属二磷酸钠纳米颗粒
- 专利标题： METAL BISPHOSPHONATE NANOPARTICLES FOR ANTI-CANCER THERAPY AND IMAGING AND FOR TREATING BONE DISORDERS
- 专利标题（中）： 用于抗癌治疗和成像和治疗骨质疏松症的金属二磷酸钠纳米颗粒
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申请号： US14131575申请日： 2012-07-09
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公开(公告)号： US20140234210A1公开(公告)日： 2014-08-21
- 发明人: Wenbin Lin , Demin Liu , Joseph Della Rocca , Stephanie A. Kramer , Christopher Y. Poon
- 申请人： Wenbin Lin , Demin Liu , Joseph Della Rocca , Stephanie A. Kramer , Christopher Y. Poon
- 申请人地址： US NC Chapel Hill
- 专利权人： The University of North Carolina at Chapel Hill
- 当前专利权人： The University of North Carolina at Chapel Hill
- 当前专利权人地址： US NC Chapel Hill
- 国际申请： PCT/US2012/045954 WO 20120709
- 主分类号： A61K9/51
- IPC分类号： A61K9/51 ; A61K49/00 ; A61K51/12 ; A61K31/675 ; A61K9/127 ; A61K31/663
摘要：
Metal-bisphosphonate nanoparticles are disclosed. Also disclosed are pharmaceutical compositions including the metal-bisphosphonate nanoparticles, methods of preparing the metal-bisphosphonate nanoparticles and materials comprising the nanoparticles, and methods of using the compositions to treat cancer or bone-related disorders (e.g., bone-resorption-related diseases, osteoporosis, Paget's disease, and bone metastases) and as imaging agents.
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