发明申请
- 专利标题： TGR5 AGONISTS
- 专利标题（中）： TGR5激励
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申请号： US13515132申请日： 2010-08-11
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公开(公告)号： US20130303505A1公开(公告)日： 2013-11-14
- 发明人: Venkataiah Bollu , Brant Clayton Boren , Jackaline Dalgard Julien , Brenton T. Flatt , Nadia Haq , Sarah Hudson , Raju Mohan , Michael Morrissey , Benjamin Pratt
- 申请人： Venkataiah Bollu , Brant Clayton Boren , Jackaline Dalgard Julien , Brenton T. Flatt , Nadia Haq , Sarah Hudson , Raju Mohan , Michael Morrissey , Benjamin Pratt
- 国际申请： PCT/US10/45195 WO 20100811
- 主分类号： C07D487/08
- IPC分类号： C07D487/08 ; A61K31/4995 ; A61K31/496 ; A61K31/454 ; A61K31/4439 ; A61K31/4196 ; A61K31/4178 ; A61K31/4164 ; C07D295/15 ; C07D401/12 ; C07D249/12 ; C07D403/12 ; C07D233/84 ; C07D233/64 ; A61K31/5377
摘要：
TGR5 agonists of structural formula VIII(Q), wherein X, R1, R2, and R5 are defined in the specification, pharmaceutically acceptable salts thereof, compositions thereof, and use of the compounds and compositions for treating diseases. The invention also comprises use of the compounds in and for the manufacture of medicaments, particularly for treating diseases.
公开/授权文献
- US08846739B2 TGR5 agonists 公开/授权日：2014-09-30
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