发明申请
- 专利标题: INDOLIZINE INHIBITORS OF 5-LIPOXYGENASE
- 专利标题(中): 5-LIPOXYGENASE的吲哚啉抑制剂
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申请号: US13497517申请日: 2010-09-23
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公开(公告)号: US20130005721A1公开(公告)日: 2013-01-03
- 发明人: Brian Andrew Stearns , Jeffrey Roger Roppe , Timothy Andrew Parr , Nicholas Simon Stock , Deborah Volkots , John Howard Hutchinson
- 申请人: Brian Andrew Stearns , Jeffrey Roger Roppe , Timothy Andrew Parr , Nicholas Simon Stock , Deborah Volkots , John Howard Hutchinson
- 申请人地址: US CA San Diego
- 专利权人: PANMIRA PHARMACEUTICALS, LLC
- 当前专利权人: PANMIRA PHARMACEUTICALS, LLC
- 当前专利权人地址: US CA San Diego
- 国际申请: PCT/US10/49954 WO 20100923
- 主分类号: A61K31/437
- IPC分类号: A61K31/437 ; A61K31/5377 ; A61K31/4709 ; A61K31/444 ; A61K31/506 ; A61P29/00 ; A61P11/00 ; A61P9/00 ; A61P11/06 ; A61P9/10 ; A61P9/12 ; A61P25/00 ; A61P11/02 ; A61P19/02 ; A61P35/00 ; A61P3/00 ; C07D471/04
摘要:
Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of 5-lipoxygenase (5-LO). Also described herein are methods of using such 5-LO inhibitors, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions, diseases, or disorders.
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