- 专利标题： N-substituted benzene sulfonamides
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申请号： US13372126申请日： 2012-02-13
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公开(公告)号： US20120270902A1公开(公告)日： 2012-10-25
- 发明人: Martin Neitzel , Jennifer Marugg
- 申请人： Martin Neitzel , Jennifer Marugg
- 申请人地址： US CA South San Francisco
- 专利权人： ELAN PHARMACEUTICALS, INC.
- 当前专利权人： ELAN PHARMACEUTICALS, INC.
- 当前专利权人地址： US CA South San Francisco
- 主分类号： A61K31/18
- IPC分类号： A61K31/18 ; C07D211/56 ; A61K31/445 ; C07D213/42 ; A61K31/4406 ; C07D207/14 ; A61K31/40 ; C07D277/28 ; A61K31/426 ; C07D417/12 ; A61K31/4439 ; C07D317/46 ; A61K31/357 ; C07D319/16 ; C07D311/58 ; A61K31/353 ; A61K31/4409 ; C07D233/52 ; A61K31/4168 ; C07D307/52 ; A61K31/341 ; C07D209/14 ; A61K31/4045 ; A61P25/28 ; A61P7/04 ; C07C311/17 ; A61P25/00 ; C07D231/06 ; A61K31/415 ; C07C311/20
摘要：
The invention provides N-substituted benzenesulfonamides for use in treating or preventing cognitive disorders, such as Alzheimer's Disease. Compounds of particular interest are defined by Formula (I), wherein R1, R2, R3, R4, and R3′, are as described in the specification. The invention also encompasses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of treating cognitive disorders, including Alzheimer's disease using compounds of Formula (I).
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