发明申请
- 专利标题： SYSTEMS AND METHODS FOR ENHANCING VACCINE EFFICACY
- 专利标题（中）： 用于增强疫苗效能的系统和方法
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申请号： US13139220申请日： 2009-12-14
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公开(公告)号： US20110300129A1公开(公告)日： 2011-12-08
- 发明人: Richard P. Phipps , Tatiana Margarita Garcia-Bates
- 申请人： Richard P. Phipps , Tatiana Margarita Garcia-Bates
- 申请人地址： US NY Rochester
- 专利权人： UNIVERSITY OF ROCHESTER
- 当前专利权人： UNIVERSITY OF ROCHESTER
- 当前专利权人地址： US NY Rochester
- 国际申请： PCT/US2009/067892 WO 20091214
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61P39/00 ; C12N5/078 ; A61P31/04 ; A61K39/02 ; A61P37/04 ; A61P31/12 ; A61P33/00 ; A61K45/06 ; A61K39/12
摘要：
Pharmaceutical compositions of the invention include an antigen or a nucleic acid molecule encoding the antigen; one or both of a PPAR ligand and an RxR ligand; and a pharmaceutically suitable carrier. The pharmaceutical composition can optionally include a mitogen or other additives. Also disclosed are methods of inducing B cell differentiation and promoting an immune response against an antigen.
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