发明申请
- 专利标题: HEPATOCYTE GROWTH FACTOR (HGF) BINDING PROTEINS
- 专利标题(中): HEPATOCYTE生长因子(HGF)结合蛋白
-
申请号: US11757094申请日: 2007-06-01
-
公开(公告)号: US20080038257A1公开(公告)日: 2008-02-14
- 发明人: May Han , S. Wright , William Winston , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris
- 申请人: May Han , S. Wright , William Winston , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07H21/04 ; C07K16/00 ; C12N15/00 ; C12N5/00 ; C12P21/00
摘要:
The present invention provides a family of binding proteins that bind and neutralize the activity of hepatocyte growth factor (HGF), in particular human HGF. The binding proteins can be used as diagnostic and/or therapeutic agents. With regard to their therapeutic activity, the binding proteins can be used to treat certain HGF responsive disorders, for example, certain HGF responsive tumors.
公开/授权文献
- US07659378B2 Hepatocyte growth factor (HGF) binding antibody 公开/授权日:2010-02-09
信息查询