发明申请
US20050191323A1 Pharmaceutical formulations comprising paclitaxel, derivatives and pharmaceutically acceptable salts thereof
审中-公开
包含紫杉醇，其衍生物和药学上可接受的盐的药物制剂
- 专利标题： Pharmaceutical formulations comprising paclitaxel, derivatives and pharmaceutically acceptable salts thereof
- 专利标题（中）： 包含紫杉醇，其衍生物和药学上可接受的盐的药物制剂
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申请号： US11100681申请日： 2005-04-07
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公开(公告)号： US20050191323A1公开(公告)日： 2005-09-01
- 发明人: Hongming Chen
- 申请人： Hongming Chen
- 主分类号： G01N33/15
- IPC分类号： G01N33/15 ; A61K9/06 ; A61K9/08 ; A61K9/10 ; A61K9/107 ; A61K31/137 ; A61K31/28 ; A61K31/337 ; A61K31/4745 ; A61K45/00 ; A61K47/10 ; A61K47/14 ; A61K47/18 ; A61K47/26 ; A61K47/34 ; A61P35/00 ; A61P43/00 ; A61K38/10 ; A61K31/704 ; A61K31/7072
摘要：
The invention concerns paclitaxel solubilizers and formulations thereof with a high propensity to dissolve paclitaxel. The formulations of the invention reduce or obviate the need for the disadvantageous excipient Cremophor® EL. The formulations of the invention are useful for administering paclitaxel, its derivatives, or pharmaceutically acceptable salts of such derivatives to patients in need thereof. The formulations of the invention are suitable for parenteral, oral, local, or transdermal administration to mammals including humans, particularly for intravenous delivery.
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