发明申请
- 专利标题： Prodrugs of thrombin inhibitors
- 专利标题（中）： 凝血酶抑制剂的前药
-
申请号： US10776245申请日： 2004-02-12
-
公开(公告)号： US20040162410A1公开(公告)日： 2004-08-19
- 发明人: Thomas Antonsson , David Gustafsson , Kurt-Jurgen Hoffmann , Jan-Erik Nystrom , Henrik Sorensen , Mikael Sellen
- 申请人： AstraZeneca AB
- 申请人地址： SE Sodertalje
- 专利权人： AstraZeneca AB
- 当前专利权人： AstraZeneca AB
- 当前专利权人地址： SE Sodertalje
- 优先权： GB9526273.9 19951221; SE9600556-6 19960215; SE9704542-1 19971205; WOPCT/SE98/02191 19981201
- 主分类号： C07K005/06
- IPC分类号： C07K005/06 ; A61K038/05
摘要：
There is provided compounds of formula I, R1O(O)CnullCH2null(R)Cgl-Aze-Pab-R2nullnullI wherein R1 and R2 have meanings given in the description, which are useful as prodrugs of inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (eg thrombosis) or as anticoagulants.
公开/授权文献
- US07354905B2 Prodrugs of thrombin inhibitors 公开/授权日：2008-04-08
信息查询
