Invention Grant
- Patent Title: Heteroaryl-biphenyl amines for the treatment of PD-L1 diseases
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Application No.: US17071056Application Date: 2020-10-15
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Publication No.: US11866429B2Publication Date: 2024-01-09
- Inventor: Pingchen Fan , Christopher W. Lange , Rebecca M. Lui , Darren J. McMurtrie , Ryan J. Scamp , Ju Yang , Yibin Zeng , Penglie Zhang
- Applicant: CHEMOCENTRYX, INC.
- Applicant Address: US CA Mountain View
- Assignee: CHEMOCENTRYX, INC.
- Current Assignee: CHEMOCENTRYX, INC.
- Current Assignee Address: US CA Thousand Oaks
- Agent Amy C. Madl
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K45/06
Abstract:
Compounds are provided that are useful as immunomodulators. The compounds have the Formula (I)
including stereoisomers and pharmaceutically acceptable salts thereof, wherein R2a, R2b, R3, R3a, R4, R6, R7, R8, A, Z, X1 and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
including stereoisomers and pharmaceutically acceptable salts thereof, wherein R2a, R2b, R3, R3a, R4, R6, R7, R8, A, Z, X1 and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
Public/Granted literature
- US20210130347A1 HETEROARYL-BIPHENYL AMINES FOR THE TREATMENT OF PD-L1 DISEASES Public/Granted day:2021-05-06
Information query
