A signal interference avoidance method includes, when the self-interference occurs for the UE connected concurrently to a first network device and a second network device, transmitting first interference avoidance indication information to the second network device. The first interference avoidance indication information is used to enable the second network device to communicate with the UE through a first time-domain resource and/or a first frequency-domain resource. The first interference avoidance indication information includes identification information about the UE.