An image pickup unit includes: a metal barrel holding an objective lens; a substrate barrel formed of a circuit formed product having insulation property; an image sensor having a chip size package; plural electrodes formed in a penetrating manner from an inside of a substrate barrel to a proximal end side in an exposed manner, the plural electrodes being electrically connected to an image sensor in the substrate barrel; an electric conductive portion formed on an outer surface of the substrate barrel, having an insulation property with respect to the metal barrel, and having a predetermined creepage distance by which a current such as static electricity can be discharged; a ground electrode electrically connected to the electric conductive portion; and a cable provided with plural wires connected to a ground wire connected to the ground electrode and plural wires connected to the plural electrodes.