A multi-tray medication dispensing apparatus and a method of use provides secure storage and dispensing of controlled substances and supplemental/alternative medication while providing remote assistance and monitoring. The apparatus includes at least two motorized medication trays for automatic dispensing of medication. Medication tray compartments can be filled manually or filled by inserting a prefilled blister pack containing sealed medication. The apparatus further comprises a secure tamper resistant housing, plurality of sensors, an optional reclamation safe, and a wireless communication module to notify remote operators of suspected illegal/unauthorized access. The apparatus can be configured in different form factors including, a portable desktop configuration, a wearable configuration designed for attaching to a person's wrist, arm, foot, etc. The apparatus can dispense a controlled substance or supplemental/alternative medication based upon a dispensing schedule and/or inputs from the user, wherein the supplemental/alternative medication is alternatively dispensed to control addition and/or proper use.