The present disclosure discloses a pixel drive circuit and a display panel. The pixel drive circuit includes a Micro-LED, a cathode of which is grounded; a light-emitting control circuit connected with an anode of the Micro-LED and configured to control an emission time of the Micro-LED; a current control circuit connected with the light-emitting control circuit and configured to output a preset current to the light-emitting control circuit to control the Micro-LED to work under a set current density, and luminance efficiency of the Micro-LED under the set current density is greater than a set threshold value.