- 专利标题: Self-assembling peptides comprising non-Ionic polar amino acids
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申请号: US16865734申请日: 2020-05-04
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公开(公告)号: US11497833B2公开(公告)日: 2022-11-15
- 发明人: Eun Seok Gil , Marika Rioult , Keiji Nagano , Karl Patrick Gilbert , Toshiro Kiyofuji , Yuya Hasegawa
- 申请人: 3-D Matrix, Ltd.
- 申请人地址: JP Tokyo
- 专利权人: 3-D Matrix, Ltd.
- 当前专利权人: 3-D Matrix, Ltd.
- 当前专利权人地址: JP Tokyo
- 代理机构: IP Supra, PLLC
- 代理商 Constantine Linnik; Beth L. Smiley
- 主分类号: A61L27/52
- IPC分类号: A61L27/52 ; A61L27/22 ; C07K14/00 ; C07K7/08 ; A61L27/54
摘要:
Compositions, peptide solutions and macroscopic scaffolds of self-assembling peptides consisting essentially of non-ionic, polar amino acids are provided. Particular peptides include those comprising, or consisting essentially of, serine, threonine, tyrosine, cysteine, glutamine, asparagine, methionine, tryptophan, hydroxy-proline, and combinations thereof. Methods of sterilizing the self-assembling peptides, and scaffolds comprising the peptides are also provided.
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