Invention Grant
- Patent Title: Amino indole compounds useful as TLR inhibitors
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Application No.: US16955166Application Date: 2018-12-19
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Publication No.: US11306092B2Publication Date: 2022-04-19
- Inventor: Alaric J. Dyckman , Dharmpal S. Dodd , Christopher P. Mussari , David R. Tortolani , Tasir Shamsul Haque , Shoshana L. Posy
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- Agent Gary Greenblatt
- International Application: PCT/US2018/066344 WO 20181219
- International Announcement: WO2019/126242 WO 20190627
- Main IPC: C07D401/04
- IPC: C07D401/04 ; A61K31/4439 ; C07D471/10 ; C07D209/12 ; C07D401/14 ; C07D403/04 ; C07D409/14 ; C07D413/12 ; C07D471/04

Abstract:
Disclosed are compounds of Formula (I) or salts thereof, wherein G, R1, R5, R7, R8, and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.
Public/Granted literature
- US20200339581A1 AMINO INDOLE COMPOUNDS USEFUL AS TLR INHIBITORS Public/Granted day:2020-10-29
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