Invention Grant
- Patent Title: Focusing light inside scattering media with magnetic particle guided wavefront shaping
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Application No.: US16058498Application Date: 2018-08-08
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Publication No.: US11156960B2Publication Date: 2021-10-26
- Inventor: Haowen Ruan , Jacob Berlin , Tom Haber , Changhuei Yang
- Applicant: California Institute of Technology
- Applicant Address: US CA Pasadena
- Assignee: California Institute of Technology
- Current Assignee: California Institute of Technology
- Current Assignee Address: US CA Pasadena
- Agency: Gates & Cooper LLP
- Main IPC: G01N21/47
- IPC: G01N21/47 ; G03H1/04 ; G01N33/483 ; G03H1/22 ; G03H1/00

Abstract:
A magnetic field controlled guidestar for focusing light deep inside scattering media using optical phase conjugation. Compared with the optical and ultrasonic field, the magnetic field has an exceptional penetration depth. The magnetic particle guidestar has a high light-tagging efficiency, good biocompatibility, and a small diameter which enables a sharp and bright focusing deep inside biological tissue. This new method can benefit a wide range of biomedical applications including deep-tissue imaging, neural modulation, and targeted photothermal and photodynamic therapies.
Public/Granted literature
- US20190064736A1 FOCUSING LIGHT INSIDE SCATTERING MEDIA WITH MAGNETIC PARTICLE GUIDED WAVEFRONT SHAPING Public/Granted day:2019-02-28
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