Invention Grant
- Patent Title: Pyrrolopyrimidine nucleosides and analogs thereof
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Application No.: US16533194Application Date: 2019-08-06
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Publication No.: US10941175B2Publication Date: 2021-03-09
- Inventor: John Henry Bougher, III , Ramamurty V S Changalvala , Aaron Leigh Downey , John C. Drach , Ernest Randall Lanier, Jr. , Andrew Louis McIver , Bradley David Robertson , Dean Wallace Selleseth , Phiroze Behram Sethna , Leroy Townsend , Roy W. Ware
- Applicant: Chimerix, Inc. , The Regents of the University of Michigan
- Applicant Address: US NC Durham; US MI Ann Arbor
- Assignee: Chimerix, Inc.,The Regents of the University of Michigan
- Current Assignee: Chimerix, Inc.,The Regents of the University of Michigan
- Current Assignee Address: US NC Durham; US MI Ann Arbor
- Agency: Cooley LLP
- Agent Ivor R. Elrifi; Heidi A. Erlacher
- Priority: GB1606645 20160415
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K31/70 ; C07H19/14 ; C07D239/70 ; C07H19/16 ; A61K31/7052 ; A61K31/706 ; A61K31/7064
Abstract:
The present disclosure provides pyrrolopyrimidine nucleoside analogs of the Formula I, Formula IA, Formula IB, or Formula II and phospholipid conjugates and pharmaceutical compositions thereof wherein Rc and A are defined herein. Also presented are methods of treating and/or preventing viral infection and/or viral infection-associated disease or disorder with one or more compounds of Formula I, Formula IA, Formula IB, or Formula II.
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