Invention Grant
- Patent Title: Heteroarylhydroxypyrimidinones as agonists of the APJ receptor
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Application No.: US16061365Application Date: 2016-12-15
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Publication No.: US10669261B2Publication Date: 2020-06-02
- Inventor: Michael C. Myers , R. Michael Lawrence , Donna M. Bilder , Wei Meng , Zulan Pi , Robert Paul Brigance , Heather Finlay
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristl-Myers Squibb Company
- Current Assignee: Bristl-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Hong Liu
- International Application: PCT/US2016/066750 WO 20161215
- International Announcement: WO2017/106396 WO 20170622
- Main IPC: A61K31/506
- IPC: A61K31/506 ; A61K31/513 ; C07D403/04 ; C07D413/04 ; C07D413/14 ; C07D417/04 ; C07D417/14 ; A61P9/04 ; A61P9/10 ; A61P9/12 ; A61P9/00
Abstract:
The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments, in particular for treating cardiovascular disorders.
Public/Granted literature
- US20180362508A1 HETEROARYLHYDROXYPYRIMIDINONES AS AGONISTS OF THE APJ RECEPTOR Public/Granted day:2018-12-20
Information query
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