A wheel deburring device includes a machine frame, a wheel delivery and positioning mechanism mounted in the frame, and a brush for brushing off burrs from a wheel. The brush is movably mounted to the frame through a rising and falling plate and a sliding plate rack connected with the plate via first guide rails, the brush being able to rotate by a servo motor mounted in the frame and to rise and fall by a rising and falling cylinder. A first servo electric cylinder is mounted so that the first cylinder can adjust angles of the brush. A second servo electric cylinder is fixed at one side of the rising and falling plate, and its output end is connected with the rack so that the second cylinder can adjust positions of the brush through first guide rails.