- 专利标题: Tunable nitric oxide-releasing macromolecules having multiple nitric oxide donor structures
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申请号: US14961133申请日: 2015-12-07
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公开(公告)号: US10196349B2公开(公告)日: 2019-02-05
- 发明人: Mark Schoenfisch , Yuan Lu , Nathan Stasko , Jian Bao
- 申请人: The University of North Carolina at Chapel Hill , Novan, Inc.
- 申请人地址: US NC Chapel Hill US NC Morrisville
- 专利权人: The University of North Carolina at Chapel Hill,Novan, Inc.
- 当前专利权人: The University of North Carolina at Chapel Hill,Novan, Inc.
- 当前专利权人地址: US NC Chapel Hill US NC Morrisville
- 代理机构: Myers Bigel, P.A.
- 主分类号: C07C281/20
- IPC分类号: C07C281/20 ; A61K31/655 ; A61K9/14 ; C07C291/02 ; C07C247/10
摘要:
Provided here are nitric oxide-releasing compounds that include at least two different NO donor functional groups of the same class. In some embodiments, such nitric oxide-releasing compounds are macromolecules such as dendrimer and co-condensed silica. Pharmaceutical compositions, wound dressings, kits and methods of treatments are also provided herein.
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