The invention discloses a testing system and method for a vertical pipe pressure sensor. The system comprises a hydraulic testing tool and a data collection system, wherein the hydraulic testing toolcomprises a union tool used for installing the vertical pipe pressure sensor, and a hydraulic pump used for providing a preset pressure value for the vertical pipe pressure sensor; the union tool is connected with the hydraulic pump; the data collection system comprises a safety box and an industrial personal computer, wherein the safety box is used for carrying out conversion processing on an electric signal output by the vertical pipe pressure sensor under a preset pressure value; the industrial personal computer is used for determining the practical pressure value of the vertical pipe pressure sensor according to the signal subjected to conversion processing, comparing the practical pressure value with the preset pressure value, and determining the reliability of the vertical pipe pressure sensor according to a comparison result; the safety box is independently connected with the vertical pipe pressure sensor and the industrial personal computer on the union. By use of the testing system and method for the vertical pipe pressure sensor, the vertical pipe pressure sensor with low reliability can be effectively screened.