The invention provides a hydrophilic lipid composition containing fluid marrow fat, a liposoluble substance B and an emulsifying agent. The fluid marrow fat is selected from linolenic acid and mediumchain triglyceride, the emulsifying agent is selected from phospholipid and sucrose fatty acid ester, and the liposoluble substance B is selected from xanthophyll ester, xanthophyll, a coenzyme Q, carotene, astaxanthin, lycopene and soy isoflavone. The hydrophilic lipid composition is mixed with a water-based fluid, shaking is carried out, and uniform and stable emulsion can be formed within 1-5 seconds, rapid and convenient blending of the lipid composition with the water-based fluid is facilitated, the hydrophilic lipid composition has the advantage of being capable of immediately blended and used, oral absorption and utilization of the fluid marrow fat and the liposoluble substance B are also facilitated, and immediate blending and use of a user is greatly facilitated. The invention also provides a composition thereof, a packaging composition thereof, a blending and application method as well as application of the composition in preparation of medicines, food with special medicinalapplication and formula, health food or nutritional food.