The invention discloses an anti-interference method and device for wireless perception based on channel state information. The method comprises the following steps of detecting each received data packet, and acquiring a data packet subjected to radio frequency interference; extracting distortion sub-carriers in the data packet subjected to radio frequency interference to obtain sub-carriers to beprocessed; and carrying out correlation processing on the sub-carriers to be processed, and eliminating the radio-frequency interference borne by the distortion sub-carriers. The device is used for executing the method. According to the anti-interference method and device for wireless perception based on the channel state information, which are provided by the invention, through detecting the received data packets, acquiring the data packet subjected to radio frequency interference, extracting the distortion sub-carriers, acquiring the sub-carriers to be processed, carrying out correlation processing on the sub-carriers to be processed, and eliminating the distortion of the distortion sub-carriers, the anti-interference capability of a wireless perception application based on a Wi-Fi signal is enhanced, and the accuracy of wireless perception is improved.