The invention discloses an automatic PCB alignment detection device. The automatic PCB alignment detection device comprises a foundation, a supporting board, a first servo motor, a transverse arm, a second servo motor, a leading screw, a feeding nut, a linear guide rail, a moving board, a tension and pressure sensor, a bottom board, a pinch roller assembly and a controller, during work, the bottom plate and a PCB are mounted at an upper end of the supporting board, the first servo motor is controlled by the controller for driving the transverse arm to rotate for 90 DEG, then, the feeding nut is driven by the second servo motor through the leading screw to move forwards to make a pinch roller realize translation on the PCB, if the PCB or the bottom plate is not mounted in place, the pinch roller under the reaction force generates a certain push force onto the tension and pressure sensor, when the set force is realized, a power source is cut through the controller, and alarm is carried out. The detection device is advantaged in that the structure is simple, whether the PCB and the bottom plate fit can be automatically checked, the PCB and the bottom plate are made to tightly fit under the pressure effect of the pinch roller, not only can a check accuracy rate be improved, but also labor intensity of workers is reduced, and production efficiency is improved.