The invention belongs to the technical field of preparation of multistage structure tungsten particle reinforced aluminum base composite materials, and in particular, relates to a preparation method of a multistage structure tungsten particle reinforced aluminum base composite material. The multistage structure tungsten particle reinforced aluminum base composite material is prepared by using a high-energy ball milling-low-energy mixing-hot isostatic pressing process. The composite material uses Al as a basal body and an Al-W agglomerate as a reinforcement phase to form a cluster structure; the basal body material between clusters has a larger deformation area, so that the phenomenon of dispersion distribution of the tungsten reinforcement phase in a traditional Al-W composite material is improved, the plasticity of the composite material is improved, and the Al-W interface bonding property is improved; and the rough surface state of the clusters improves the interface bonding force between the clusters and the basal body and improves the comprehensive performances of the composite material. The composite material has such advantages as high compactness, high strength, good plasticity and high use temperature, and is a light-mass and high-strength composite material, and is higher in application potential.