The invention relates to a five-wheel automobile driving mechanism. The five-wheel automobile driving mechanism is composed of a protection seat, two side handrail operating levers and a transverse slide rail apparatus, wherein a left protection surface and a right protection surface of the protection seat are provided with a collision buffer sandwich layer, the two side handrail operating levers are electromechanically connected with an electric power-assisted steering apparatus, the transverse slide rail apparatus enables the protection seat to slide among a left position, a middle position and a right position in a cab and to be temporarily fixed, a driving position of a driver can be flexibly changed according to the requirements of traffic laws of different countries, a vehicle is freer and more comfortable, and the automobile driving safety is remarkably improved.