The invention relates to an electronic control adjusting type intake and exhaust guide system of a double-reaction-chamber preheating catalytic oxidation device. The electronic control adjusting type intake and exhaust guide system comprises an intake manifold, an intake branch, intake flared pipes, two intake cavities, two abreast reaction chambers, an exhaust cavity and an exhaust manifold. A first guide plate is arranged in each intake flared pipe, a second guide plate is arranged in each intake cavity, and a third guide plate is arranged in the exhaust cavity. A PLC (programmable logic controller) is added, a first electronic control adjusting mechanism is added on the outer wall of each intake flared pipe, and a second electronic control adjusting mechanism is added on the sidewall of each intake cavity. The first guide plates in the intake flared pipes are adjusted and controlled to rotate by the first electronic control adjusting mechanisms, and the second guide plates in the intake cavities are adjusted and controlled to rotate by the second electronic control adjusting mechanisms. The electronic control adjusting type intake and exhaust guide system is capable of adjusting angles of the guide plates flexibly under the actual working condition of violent intake flow fluctuation to guarantee uniform distribution of intake flow and temperature of an oxidation bed, so that device operation reliability is improved while ventilation air methane oxidation ratio is increased.