The invention belongs to the technical field of vehicle tire pressure monitor system (TPMS) calibration and specifically relates to a TPMS calibration system. The TPMS calibration system comprises a matching tool and a sensor. The matching tool is connected with the to-be-matched sensor through a wire and sends a trigger signal to the sensor through the wire. The sensor feeds identity (ID) information of the sensor back to the matching tool after receiving the trigger signal. The trigger signal given by the matching tool is transmitted to the sensor in a wired mode, so that the phenomenon that matching can not be achieved due to a small gap between tires is avoided. Meanwhile, the wired transmission mode is very reliable and accurate.