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发明公开
CN104926791A 一种埃索美拉唑钠的制备方法 有权

一种埃索美拉唑钠的制备方法
摘要：
本发明提供了一种操作简便、产率和纯度高、适合工业化生产的埃索美拉唑钠的制备方法，通过筛选特定的反应溶剂和水的加入量，及控制特定反应温度、时间和pH值，得到纯度超过99％、收率超过32％的埃索美拉唑钠。
摘要（英）：

The invention provides a preparation method of esomeprazole sodium. The method provided by the invention is simple to operate, is high in yield and purity of the esomeprazole sodium and is suitable for industrial production. A specific reactive solvent is screened, the addition amount of water is regulated, and the specific reaction temperature, time and pH value are controlled, so that the esomeprazole sodium of which the purity exceeds 99% and the yield exceeds 32% is obtained.

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