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发明公开
CN102659683A 5-烷氧基-4-羟基甲基吡唑化合物的制备方法 有权 转让

5-烷氧基-4-羟基甲基吡唑化合物的制备方法
摘要：
本发明涉及一种以简单且收率良好地制备5-烷氧基-4-羟基甲基吡唑化合物的方法。通式(3)表示的5-烷氧基-4-羟基甲基吡唑化合物的制备方法，(式中，R1表示烷基、可具有取代基的芳基等取代基，R2表示电子吸引性基团，且R3表示可具有取代基的烷基等取代基)，其包括在碱和甲醛的存在下，使通式(1)表示的吡唑化合物与通式(2)表示的化合物反应的步骤，(式中，R1和R2如上定义)L-R3 (2)(式中，L是离去基团且R3如上定义)。
摘要（英）：

The present invention relates to a process for producing a 5-alkoxy-4-hydroxymethylpyrazole compound in a simple manner and with good efficiency. A process for producing a 5-alkoxy-4-hydroxymethylpyrazole compound represented by the general formula (3) comprises reacting a pyrazole compound represented by the general formula (1) (wherein R1 is a substituent such as alkyl group, substituted or unsubstituted group or the like, and R2 is an electron withdrawing group) with a compound represented by the general formula (2): L-R3 (2) (wherein L is a leaving group and R3 is a substituent such as substituted or unsubstituted alkyl group or the like) in the presence of a base and formaldehyde.

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