The invention discloses a virtual surgical instrument with 5-free degree force feedback, which belongs to the field medical training instruments. The invention includes a control detecting system anda mechanical structure which consists of a set of feet, a base board, two columns, a roof, four reduction gears, four reduction arc teeth, four retaining plates, two scissor handles, two parallel guide rods, a set of pull rods, an operating lever, a rolling bearing, an upper beam, a lower beam, a roller and a slide block and five drive actuators. The sensor collects input information of an interactive system such as pose and operating speed of an equipment handle, while drive actuators apply a variety of force and damping effect to an equipment operator. The virtual surgery device with 5-freedegree force feedback can realize force feedback function with 5 free degrees, and the allowable human sports joints include the wrist joint, the elbow joint and the shoulder joint of the arm. With the virtual surgical instrument, the operator can perform virtual surgery actions of surgical scissors, a surgical clamp, a scalpel and a surgical abrasion drill, etc.