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发明公开
CN101070322A 7－(4－肟基－3－氨基－1－哌啶基)新喹啉羧酸衍生物及其制备方法和医药用途 无效 - 撤回

7－(4－肟基－3－氨基－1－哌啶基)新喹啉羧酸衍生物及其制备方法和医药用途
摘要：
本发明涉及7－(4－肟基－3－氨基－1－哌啶基)新喹啉羧酸衍生物及其制备方法和医药用途；涉及含有它们的抗菌剂和饲料添加剂，更具体讲，本发明涉及式(I)的新氟喹诺酮和萘啶酮甲酸衍生物，其在喹诺酮核7－位上有(4－肟基－3－氨基－1－哌啶基)取代基，其与现有的氟喹诺酮抗菌药物相比，具有更加优越的抗革兰氏阳性菌活性和广谱抗菌活性，式中各基团定义见说明书。
摘要（英）：

This invention relates to 7 - ( 4 - isonitroso - 3 - amido - 1 - piperidyl) new quinoline carboxylic acid ramification and preparation method, and relates to the medicine use, such as antimicrobial and feed additive. More concretely, the invention relates to new fluorine Quinolone and naphthyridine ketone methanoic acid ramification as formulae (I), which has ( 4 - isonitroso - 3-amido - 1 - piperidyl) substituent group at caryo 7 position of quinolone. Comparing with existing fluorine quinolone antibacterial, the invention has superior grampositivebacteria resisting activity and broad spectrum antibacterial activity. Each group definition of the formulae is described in specification.

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