The present invention discloses a cleaning device and equipment cleaning method combined with the cleaning device; the cleaning device comprises a cleaning carrier and pressure control system; the cleaning carrier comprises a base and a shell which are combined together to form a cleaning chamber; the shell top is equipped with a guide hole and the base inside comprises a liquid channel communicated with the cleaned articles; the pressure control system is equipped with a pressure supply part communicated with the guide hole by pressure which makes the pressure control system communicated with the cleaning carrier by pressure; with the conversion between the positive and negative pressures, the pressure control system produces liquid force in the cleaning chamber and liquid channel to remove the residual material.