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公开(公告)号:US12205810B2
公开(公告)日:2025-01-21
申请号:US18352750
申请日:2023-07-14
Applicant: Thermo Fisher Scientific (Bremen) GmbH
Inventor: Hamish Stewart , Alexander Wagner , Alexander A. Makarov
IPC: H01J49/00 , G01N27/622 , H01J49/06 , H01J49/36 , H01J49/42
Abstract: An ion guide may comprise a set of plate electrodes, each plate electrode having a plurality of apertures formed therethrough. The set of plate electrodes are spatially arranged such that a relative positioning of each plurality of apertures of a respective plate electrode of the set of plate electrodes and respective adjacent plate electrodes of the set of plate electrodes defines a continuous ion flight path through the respective plurality of apertures of each plate electrode of the set of plate electrodes. The continuous ion flight path has a helical-based and/or spiral-based shape.
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公开(公告)号:US12205809B2
公开(公告)日:2025-01-21
申请号:US17854940
申请日:2022-06-30
Applicant: Bruker Switzerland AG
Inventor: Urs Steiner , Felician Muntean
IPC: H01J49/06
Abstract: A gas retaining ion guide has RF electrodes distributed about an ion region that provide an RF confinement field for ions therein. DC electrodes are also provided that extend from an entrance of the ion guide to an exit, and provide a DC electric field. The DC electrodes are further from the central axis than the RF electrodes, and each provides a gas seal between two adjacent RF electrodes. Conductive surfaces of the DC electrodes establish the DC electric field through gaps between adjacent RF electrodes, and the conductive surfaces have a distance from the central axis that changes over the length of the ion guide so as to provide an axial DC field component. The size of the DC electrode conductive surfaces and a width of the gaps between RF electrodes may be selected to ensure that ions escaping confinement through the gaps are discharged on the conductive surfaces.
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公开(公告)号:US12205807B2
公开(公告)日:2025-01-21
申请号:US17301385
申请日:2021-03-31
Applicant: Milan Pophristic
Inventor: Milan Pophristic
Abstract: An ionizing system includes a flange device for connection to a mass spectrometer or ion mobility spectrometer having the property of providing a barrier between the lower pressure region of the spectrometer and a higher pressure region substantially at atmospheric pressure, and a channel therethrough providing fluid communication between the higher and lower pressure regions. A plate device independent of the flange device which can accommodate multiple samples, such as a sample plate device, when placed over the channel in the flange device substantially seals the channel Sliding the sample plate device while in intimate contact with the flange device provides a means to sequentially and rapidly expose said samples to the opening of the channel and thus the lower pressure region. Samples are ionized when exposed to the lower pressure region in as little as one sample per second using multiple ionization methods.
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公开(公告)号:US12198919B2
公开(公告)日:2025-01-14
申请号:US17705177
申请日:2022-03-25
Applicant: Thermo Finnigan LLC
Inventor: Mikhail V. Ugarov
Abstract: It is proposed to improve transmission of ions along the curved path of an ion guide by changing the separation between adjacent multipole rods in the plane of curvature. As the separation increases along the length of the device, the ion confinement in the plane of curvature decreases. At the same time, the external field penetration from the electrodes outside of the main ion guide increases which can be used to create additional DC field gradients to facilitate ion confinement and motion through the ion guide.
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公开(公告)号:US12183837B2
公开(公告)日:2024-12-31
申请号:US17445969
申请日:2021-08-26
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Sayaka Takatsuka , Hiroshi Kobayashi
IPC: H01L31/02 , H01J49/02 , H01J49/06 , H01L31/0224 , H01L31/107
Abstract: An embodiment of the present disclosure relates to a detector that includes an AD and detects charged particles or light, and enables speeding up of response of the detector without changing a structure of the AD that limits the response of the detector. A drive circuit of the AD includes a first capacitor and a first resistor. Both the first capacitor and the first resistor are connected in series to the AD in a state where both terminals are set to have the same potential. This configuration reduces the apparent capacitance of the AD and speeds up the response of the entire detector including the drive circuit.
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公开(公告)号:US12176199B2
公开(公告)日:2024-12-24
申请号:US17616495
申请日:2020-05-11
Applicant: Leybold GmbH
Inventor: Yessica Brachthaeuser , Thorsten Benter , Marco Thinius , Michel Aliman
Abstract: The invention relates to an ionization device with an ionization space formed in a container, an inlet system for supplying a gas to be ionized to the ionization space, an electron source having at least one filament for supply of an electron beam to the ionization space, and an outlet system for letting the ionized gas out of the ionization space. Electron optics having at least two electrodes are disposed between the filament and the ionization space.
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公开(公告)号:US12159779B2
公开(公告)日:2024-12-03
申请号:US17269813
申请日:2019-08-20
Applicant: BC MACHINING TECHNOLOGIES INC.
Inventor: Eugene Kokbas
Abstract: Methods and apparatus are disclosed for producing a filament assembly with a flat frame. A frame holder is mounted to a lathe and a filament applicator is to the tool holder of the lathe. The applicator is movable along the lathe axis while the frame is rotated so that filament is wound around flat frame in a series of parallel passes. A spool of filament is rotatably supported on the applicator. The filament is guided through a filament path, and a tension control device applies tension to the filament.
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公开(公告)号:US12154780B2
公开(公告)日:2024-11-26
申请号:US16878832
申请日:2020-05-20
Applicant: Thermo Fisher Scientific (Bremen) GmbH
Inventor: Alexander A. Makarov , Wilko Balschun , Jan-Peter Hauschild , Aivaras Venckus , Denis Chernyshev , Eduard V. Denisov
Abstract: The present invention provides a mass spectrometer comprising a first ion trap, a second ion trap, a lens stack for directing ions from the first ion trap to the second ion trap and a housing. The first ion trap is arranged to form a linear or curved potential well and the second ion trap is an electrostatic ion trap, for example, an orbital ion trap, arranged to form an annular potential well. The mass spectrometer further comprises a unitary insert comprising a first cavity which holds the lens stack and a second cavity which holds the second ion trap, wherein the insert is inserted within the housing.
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公开(公告)号:US20240339314A1
公开(公告)日:2024-10-10
申请号:US18578838
申请日:2022-07-08
Applicant: Micromass UK Limited
Inventor: Jason Lee Wildgoose
CPC classification number: H01J49/406 , H01J49/0031 , H01J49/061
Abstract: A multi-reflecting time of flight mass spectrometer (8) comprising: a mass filter or mass separator (6); an ion accelerator (14) for pulsing packets of ions; ion mirrors (10) arranged to receive the ions from the ion accelerator (14) and reflect them in a first dimension (x-dimension) between the ion mirrors (10) as the ions travel in a second dimension (z-dimension); first (20) and second (22) ion reflectors arranged such that when they are both activated they reflect the ions back and forth in the second dimension; an ion detector (16) arranged to receive the ions, when a first of the ion reflectors (20,22) is deactivated; and control circuitry configured to: control the ion accelerator (14) to perform a first pulse sequence that pulses a first plurality of packets of ions into the ion mirrors (10); control the reflectors (20,22) such that ions in said plurality of packets are reflected back and forth in the second dimension by the reflectors (20,22) at the same time; and control the range of mass to charge ratios that is able to be transmitted by the mass filter or mass separator (6) to the ion accelerator (14), and the timings at which the first reflector (20) is activated and deactivated, such that substantially all of the ions from said plurality of packets of ions undergo the same number of reflections in the second dimension before being received at the detector (16).
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公开(公告)号:US12112935B2
公开(公告)日:2024-10-08
申请号:US17613796
申请日:2020-05-29
Applicant: Micromass UK Limited
Inventor: Kevin Giles , Jakub Ujma , James Harrison , Bharat Chande , Graham Scambler
IPC: H01J49/06 , G01N27/622 , H01J49/02
CPC classification number: H01J49/065 , G01N27/622 , H01J49/022 , H01J49/025
Abstract: An ion guide or ion trap that comprises a plurality of electrodes (102) is disclosed. The ion guide or ion trap includes a detector (205) that can detect light or particles (114) emitted from the ion guide or ion trap due to electrical breakdown, and a control circuit (111) that can control the ion guide or ion trap in response to the detector (205) detecting light or particles (114) emitted from the ion guide or ion trap.
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