Ion guide
    1.
    发明授权

    公开(公告)号:US12205810B2

    公开(公告)日:2025-01-21

    申请号:US18352750

    申请日:2023-07-14

    Abstract: An ion guide may comprise a set of plate electrodes, each plate electrode having a plurality of apertures formed therethrough. The set of plate electrodes are spatially arranged such that a relative positioning of each plurality of apertures of a respective plate electrode of the set of plate electrodes and respective adjacent plate electrodes of the set of plate electrodes defines a continuous ion flight path through the respective plurality of apertures of each plate electrode of the set of plate electrodes. The continuous ion flight path has a helical-based and/or spiral-based shape.

    Gas retaining ion guide with axial acceleration

    公开(公告)号:US12205809B2

    公开(公告)日:2025-01-21

    申请号:US17854940

    申请日:2022-06-30

    Abstract: A gas retaining ion guide has RF electrodes distributed about an ion region that provide an RF confinement field for ions therein. DC electrodes are also provided that extend from an entrance of the ion guide to an exit, and provide a DC electric field. The DC electrodes are further from the central axis than the RF electrodes, and each provides a gas seal between two adjacent RF electrodes. Conductive surfaces of the DC electrodes establish the DC electric field through gaps between adjacent RF electrodes, and the conductive surfaces have a distance from the central axis that changes over the length of the ion guide so as to provide an axial DC field component. The size of the DC electrode conductive surfaces and a width of the gaps between RF electrodes may be selected to ensure that ions escaping confinement through the gaps are discharged on the conductive surfaces.

    Multi-mode ionization apparatus and uses thereof

    公开(公告)号:US12205807B2

    公开(公告)日:2025-01-21

    申请号:US17301385

    申请日:2021-03-31

    Inventor: Milan Pophristic

    Abstract: An ionizing system includes a flange device for connection to a mass spectrometer or ion mobility spectrometer having the property of providing a barrier between the lower pressure region of the spectrometer and a higher pressure region substantially at atmospheric pressure, and a channel therethrough providing fluid communication between the higher and lower pressure regions. A plate device independent of the flange device which can accommodate multiple samples, such as a sample plate device, when placed over the channel in the flange device substantially seals the channel Sliding the sample plate device while in intimate contact with the flange device provides a means to sequentially and rapidly expose said samples to the opening of the channel and thus the lower pressure region. Samples are ionized when exposed to the lower pressure region in as little as one sample per second using multiple ionization methods.

    Ion guide geometry improvements
    4.
    发明授权

    公开(公告)号:US12198919B2

    公开(公告)日:2025-01-14

    申请号:US17705177

    申请日:2022-03-25

    Abstract: It is proposed to improve transmission of ions along the curved path of an ion guide by changing the separation between adjacent multipole rods in the plane of curvature. As the separation increases along the length of the device, the ion confinement in the plane of curvature decreases. At the same time, the external field penetration from the electrodes outside of the main ion guide increases which can be used to create additional DC field gradients to facilitate ion confinement and motion through the ion guide.

    Detector for detecting charged particles or light

    公开(公告)号:US12183837B2

    公开(公告)日:2024-12-31

    申请号:US17445969

    申请日:2021-08-26

    Abstract: An embodiment of the present disclosure relates to a detector that includes an AD and detects charged particles or light, and enables speeding up of response of the detector without changing a structure of the AD that limits the response of the detector. A drive circuit of the AD includes a first capacitor and a first resistor. Both the first capacitor and the first resistor are connected in series to the AD in a state where both terminals are set to have the same potential. This configuration reduces the apparent capacitance of the AD and speeds up the response of the entire detector including the drive circuit.

    Method and apparatus for producing filament array

    公开(公告)号:US12159779B2

    公开(公告)日:2024-12-03

    申请号:US17269813

    申请日:2019-08-20

    Inventor: Eugene Kokbas

    Abstract: Methods and apparatus are disclosed for producing a filament assembly with a flat frame. A frame holder is mounted to a lathe and a filament applicator is to the tool holder of the lathe. The applicator is movable along the lathe axis while the frame is rotated so that filament is wound around flat frame in a series of parallel passes. A spool of filament is rotatably supported on the applicator. The filament is guided through a filament path, and a tension control device applies tension to the filament.

    MASS SPECTROMETER HAVING HIGH SAMPLING DUTY CYCLE

    公开(公告)号:US20240339314A1

    公开(公告)日:2024-10-10

    申请号:US18578838

    申请日:2022-07-08

    CPC classification number: H01J49/406 H01J49/0031 H01J49/061

    Abstract: A multi-reflecting time of flight mass spectrometer (8) comprising: a mass filter or mass separator (6); an ion accelerator (14) for pulsing packets of ions; ion mirrors (10) arranged to receive the ions from the ion accelerator (14) and reflect them in a first dimension (x-dimension) between the ion mirrors (10) as the ions travel in a second dimension (z-dimension); first (20) and second (22) ion reflectors arranged such that when they are both activated they reflect the ions back and forth in the second dimension; an ion detector (16) arranged to receive the ions, when a first of the ion reflectors (20,22) is deactivated; and control circuitry configured to: control the ion accelerator (14) to perform a first pulse sequence that pulses a first plurality of packets of ions into the ion mirrors (10); control the reflectors (20,22) such that ions in said plurality of packets are reflected back and forth in the second dimension by the reflectors (20,22) at the same time; and control the range of mass to charge ratios that is able to be transmitted by the mass filter or mass separator (6) to the ion accelerator (14), and the timings at which the first reflector (20) is activated and deactivated, such that substantially all of the ions from said plurality of packets of ions undergo the same number of reflections in the second dimension before being received at the detector (16).

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