公开(公告)号：US11633533B2

公开(公告)日：2023-04-25

申请号：US16839983

申请日：2020-04-03

申请人： Smith & Nephew, Inc.

发明人： William W. Gregory ,  Felix Clarence Quintanar

IPC分类号： A61M35/00 ,  A61M1/00 ,  A61M27/00 ,  A61F13/00 ,  A61F13/02

摘要： Embodiments of a reduced pressure system and methods for operating the system are disclosed. In some embodiments, the system can include one or more processors responsible for various functions associated with various levels of responsiveness, such as interfacing with a user, controlling a vacuum pump, providing network connectivity, etc. The system can present GUI screens for controlling and monitoring its operation. The system can determine and monitor flow of fluid in the system by utilizing one or more of the following: monitoring the speed of a pump motor, monitoring flow of fluid in a portion of a fluid flow path by using a calibrated fluid flow restrictor, and monitoring one or more characteristics of the pressure pulses. The system can provide external connectivity for accomplishing various activities, such as location tracking of the system, compliance monitoring, tracking of operational data, remote selection and adjustment of therapy settings, etc.

公开(公告)号：US11607244B2

公开(公告)日：2023-03-21

申请号：US16903633

申请日：2020-06-17

申请人： SRGI HOLDINGS, LLC

发明人： Edward Knowlton

IPC分类号： A61B17/322 ,  A61B17/3205 ,  A61B17/3209 ,  A61M5/46 ,  A61M35/00 ,  A61B90/00 ,  A61B17/20 ,  A61B17/32 ,  A61B17/00 ,  A61B17/30 ,  A61M37/00

摘要： Systems, instruments, and methods for minimally invasive procedures including one or more of fractional resection, fractional lipectomy, fractional skin grafting, fractional scar revision, and/or fractional tattoo removal are described. Embodiments include instrumentation comprising a scalpet assembly coupled to a carrier, and the scalpet assembly includes a scalpet array. The scalpet array includes one or more scalpets configured for fractional resection, fractional lipectomy, fractional skin grafting, fractional scar revision, and/or fractional tattoo removal. The system includes a vacuum component coupled to the scalpet assembly and configured to evacuate tissue from the a site. The carrier is configured to control application of a rotational force and/or a vacuum force to the scalpet assembly.

公开(公告)号：US11596779B2

公开(公告)日：2023-03-07

申请号：US17057318

申请日：2019-05-29

申请人： MORNINGSIDE VENTURE INVESTMENTS LIMITED

发明人： Ling-Kang Tong ,  Daniela Tamar Buchman ,  Jackie Joe Hancock ,  Nicholas Terzulli

IPC分类号： A61M35/00

摘要： A two-part bioactive agent delivery system includes a disposable part, a reusable part, and a solvent removal element. The disposable part includes an agent reservoir, a transdermal patch communicating with the agent reservoir and adapted to transdermally deliver the bioactive agent to a user. The transdermal patch has a bottom surface adapted to contact skin of the user, a top surface opposite the bottom surface, and a gas permeable membrane disposed over the top surface of the transdermal patch. The reusable part includes a power source and control electronics that are adapted to deliver bioactive agent dissolved in a solvent from the agent reservoir to the transdermal patch. The solvent removal element includes a gap disposed between the disposable part and the reusable part to create a flow path for gaseous solvent to flow from the gas permeable membrane to ambient air around the bioactive agent delivery system.

公开(公告)号：US20230046815A1

公开(公告)日：2023-02-16

申请号：US17409872

申请日：2021-08-24

申请人： Mark Edward Fenzl

发明人： Mark Edward Fenzl

IPC分类号： A61K36/70 ,  A61M35/00 ,  A61K36/42 ,  A61K31/015 ,  A61K31/05 ,  A61K31/22 ,  A61K31/045 ,  A61L26/00 ,  A61K36/752 ,  A61K36/899 ,  A61L2/00

摘要： An improved wound honey using a combination of buckwheat honey, honeydew honey, a natural thickening agent of blackstrap molasses and tangerine puree, and fragrance comprising lavender essential oil. The wound honey is sterilized using a flowing UV light sanitizing system. The bottles are disinfected using a combination parecetic acid, formic acid, vanillin, clove essential oil, monolaurin, aloe vera, and hydrogen peroxide disinfectant. The product comes in a container with a pump dispenser that dispenses a quantifiable amount of product. This new wound honey with pump dispenser may be used multiple times, is cheaper than manuka honey, and may be produced outside of New Zealand and Australia.

公开(公告)号：US20230037658A1

公开(公告)日：2023-02-09

申请号：US17974212

申请日：2022-10-26

申请人： E INK CORPORATION

发明人： Richard J. PAOLINI, JR. ,  Stephen J. TELFER ,  Timothy J. O'MALLEY ,  Brian D. BEAN

IPC分类号： A61M35/00

摘要： An active molecule delivery system whereby active molecules can be released on demand and/or a variety of different active molecules can be delivered from the same system and/or different concentrations of active molecules can be delivered from the same system. The invention is well-suited for delivering pharmaceuticals to patients transdermally. In some embodiments, the system includes two separate reservoirs and a mixing area thereby allowing precursors to be mixed immediately before transdermal delivery.

公开(公告)号：US11571538B2

公开(公告)日：2023-02-07

申请号：US16603169

申请日：2018-04-11

申请人： The Regents of the University of Michigan

发明人： Mark E. Meyerhoff ,  Nicolai Lehnert ,  Yu Qin ,  Andrew Hunt ,  Elizabeth J. Brisbois ,  Hang Ren

IPC分类号： A61M16/12 ,  A61M16/08 ,  A61M16/10 ,  A61M1/16 ,  A61M1/34 ,  A61M25/00 ,  A61K33/00 ,  A61M35/00

摘要： A gas delivery device includes a nitric oxide generating system. The system has a medium including a source of nitrite ions. A working electrode is in contact with the medium. A Cu(II)-ligand complex is in contact with the working electrode. A reference/counter electrode is, or a reference electrode and a counter electrode are in contact with the medium and separated from the working electrode. An inlet conduit is to deliver nitrogen gas to the medium, and an outlet conduit is to transport a stream of nitrogen gas and nitric oxide from the medium. An inspiratory gas conduit is operatively connected to the outlet conduit to introduce an oxygen-containing gas and form an output gas stream of the gas delivery device.

公开(公告)号：US20230012468A9

公开(公告)日：2023-01-12

申请号：US16585673

申请日：2019-09-27

申请人： Snails, LLC

发明人： Tammie S. Biddle

IPC分类号： A61M35/00 ,  A61K8/35 ,  A61Q3/02 ,  A61K8/365 ,  A61Q3/04 ,  A45D29/00

摘要： A treatment application garment, such as a glove or a sock, is disclosed. The garment allows for various treatments directed toward the fingers and toes, such as the fingernails and toenails. For example, each digit of the garment may contain an absorbent pad containing acetone. The hand or foot is inserted into the garment such that the nail is positioned below the absorbent pad containing the acetone, allowing the acetone to be constantly applied to the nail to remove polish therefrom. After the treatment is complete, the glove may be removed and the open end thereof tied off, thereby containing the acetone and the smell thereof within the glove. Other features and treatments are also disclosed.

公开(公告)号：US11547869B2

公开(公告)日：2023-01-10

申请号：US17231035

申请日：2021-04-15

申请人： Light Tree Ventures Holding B.V.

发明人： Alain Dijkstra

IPC分类号： A61N5/06 ,  A61M35/00

摘要： A shape compliant wearable Photo-Dynamic Therapy (PDT) pad comprises an outer layer having an outer surface adapted to be exposed to the ambient, an inner layer having an inner surface adapted to be in contact with a body of a user, a metallic sheet provided between the outer layer and the inner layer, the metallic sheet being shape compliant, and a plurality of Light Emitting Diodes (LEDs) provided between the inner layer and the outer layer. The plurality of LEDs is configured to emit electromagnetic radiation towards the body of the user. Also, the inner layer and the metallic sheet include an enclosed cavity therebetween, the metallic sheet is configured to be maintained at a negative potential, and the inner layer includes a plurality of air holes providing a passage for ambient air to enter and exit the enclosed cavity.

公开(公告)号：US11547789B2

公开(公告)日：2023-01-10

申请号：US16646464

申请日：2018-08-21

申请人： KCI Licensing, Inc.

发明人： Christopher Brian Locke ,  Justin Alexander Long ,  Kristine M. Kieswetter

IPC分类号： A61M1/00 ,  A61M35/00 ,  A61F13/02

摘要： An apparatus for treating a tissue site includes a dressing, an oxygen source, a valve, and a negative-pressure source. The dressing is configured to be sealed around the tissue site. The oxygen source is fluidly coupled to the dressing and configured to provide a low flow of oxygen. A first port of the valve is fluidly coupled to the dressing and the valve moves between a closed position preventing flow through the valve and an open position permitting flow through the valve. The negative-pressure source is fluidly coupled to a second port of the valve and provides negative pressure to the second port of the valve at a non-therapeutic level. The valve separates the negative-pressure source from the dressing and selectively opens when a positive pressure is applied on an upstream side of the valve.

公开(公告)号：US11534585B2

公开(公告)日：2022-12-27

申请号：US16594390

申请日：2019-10-07

申请人： INTERNATIONAL BUSINESS MACHINES CORPORATION

发明人： Yang Liu ,  Steven L. Wright

IPC分类号： A61M31/00 ,  A61B5/00 ,  A61K9/00 ,  A61B5/145 ,  F16K99/00 ,  A61M35/00 ,  H01M50/60

摘要： Embodiments of the present invention are directed to a liquid delivery apparatus. A non-limiting example of the apparatus includes a substrate including a cavity formed in a surface of the substrate. The apparatus can also include a membrane disposed on the surface of the substrate covering an opening of the cavity. The apparatus can also include a hydrophobic layer disposed on the membrane. The apparatus can also include a seal disposed between the membrane and the substrate, wherein the seal surrounds the opening of the cavity. The apparatus can also include an electrode layer coupled to the membrane.