公开(公告)号：US06830548B2

公开(公告)日：2004-12-14

申请号：US10255144

申请日：2002-09-24

申请人： Jean-Luc Bonnet ,  Marcel Limousin

发明人： Jean-Luc Bonnet ,  Marcel Limousin

IPC分类号： A61B508

CPC分类号： A61N1/3702 ,  A61B5/0809 ,  A61N1/36521

摘要： An active medical device to diagnose a patient respiratory profile. This device is able to measure respiratory activity and deliver a signal (26) representative of the periodicity and amplitude of the successive respiratory cycles of the patient, in particular, a of minute ventilation (MV) signal. The device is able to analyze the aforementioned signal and discriminate between various types of respiratory profiles, in particular, to diagnose a respiratory profile of the Cheyne-Stokes type. This is achieved by detecting an alternation of respiratory cycles of hyperventilation (20) separated by periods of respiratory pause (22) or periods of hypoventilation or normal ventilation (24) and, in the latter case, to discriminate between periods of respiratory pause, corresponding to a profile of the Cheyne-Stokes (CSR) type, and periods of hypoventilation or normal ventilation, corresponding to a profile of the periodic breathing (PB) type.

摘要翻译： 用于诊断患者呼吸状况的活跃医疗设备。 该装置能够测量呼吸活动并递送代表患者的连续呼吸周期，特别是每分钟通气（MV）信号的周期和幅度的信号（26）。 该装置能够分析上述信号并区分各种类型的呼吸特征，特别是诊断Cheyne-Stokes型的呼吸特征。 这是通过检测由呼吸暂停（22）或通气不足或正常通气期（24）分开的过度换气（20）的呼吸循环的交替而实现的，并且在后一种情况下，区分呼吸暂停的时间段 对应于Cheyne-Stokes（CSR）型的剖面，以及通气不足或正常通气的时期，对应于周期性呼吸（PB）型式。

公开(公告)号：US06733463B2

公开(公告)日：2004-05-11

申请号：US10145036

申请日：2002-05-15

申请人： Eeva Moilanen ,  Lauri Lehtimäki

发明人： Eeva Moilanen ,  Lauri Lehtimäki

IPC分类号： A61B508

CPC分类号： A61B5/411 ,  A61B5/082 ,  A61B5/083 ,  G01N33/0037 ,  G01N33/497 ,  Y02A50/245

摘要： A method for measuring nitric oxide concentration in exhaled air through a blow tube of a measuring equipment. The nitric oxide concentration is measured in the exhaled air flowing in the blow tube, a flow rate of the exhaled air flowing through the blow tube is measured during the exhalation and flow resistance of the blow tube is adjusted on the basis of the measured flow rate value such that the flow rate of the exhaled air substantially remains at a preset value. The method is used to diagnose an inflammatory lung disease in a patient whereby an increased nitric oxide concentration indicates an inflammatory lung disease, such as alveolitis.

摘要翻译： 通过测量设备的吹管测量呼出空气中的一氧化氮浓度的方法。 在吹送管中流出的呼出空气中测量一氧化氮浓度，在呼气期间测量流过吹管的呼出气体的流量，根据测定的流量调节吹管的流动阻力 使得呼出空气的流量基本保持在预设值。 该方法用于诊断患者的炎症性肺病，其中增加的一氧化氮浓度表示炎性肺部疾病，例如肺泡炎。

公开(公告)号：US06712770B2

公开(公告)日：2004-03-30

申请号：US10154365

申请日：2002-05-23

申请人： Yuh-Jiuan Lin ,  Hong-Ru Guo

发明人： Yuh-Jiuan Lin ,  Hong-Ru Guo

IPC分类号： A61B508

CPC分类号： A61B5/201 ,  A61B5/097 ,  A61B5/20 ,  G01N33/497 ,  G06F19/00

摘要： A breath-based diagnostic device. The device includes an array of multiple gas sensors, a database storage device and a microprocessor. The gas sensors contain material capable of reacting with volatile organic chemicals in the exhaled breath of the subject. The database storage device stores established responses to a variety of disease. The microprocessor compares the response detected by the gas sensors and the database so as to perform the diagnosis.

摘要翻译： 一种基于呼吸的诊断装置。 该装置包括多个气体传感器阵列，数据库存储装置和微处理器。 气体传感器包含能够与受试者的呼出气体中的挥发性有机化学物质反应的物质。 数据库存储设备存储针对各种疾病的已建立的响应。 微处理器比较由气体传感器和数据库检测到的响应，以进行诊断。

公开(公告)号：US06702755B1

公开(公告)日：2004-03-09

申请号：US09860089

申请日：2001-05-17

申请人： Peter Stasz ,  Terry Hudrlik

发明人： Peter Stasz ,  Terry Hudrlik

IPC分类号： A61B508

CPC分类号： A61B5/4806 ,  A61B5/0878 ,  A61B7/003

摘要： An adapter for interfacing a pyro/piezo sensor to a polysomnograph machine comprises a differential input amplifier coupled to receive the raw transducer signals from a PVDF film transducer to provide a requisite gain while rejecting common mode noise. The resulting amplified signal is filtered to separate the pyro signal from the piezo signal and the piezo signal is further applied to half-wave rectifier stages that function to remove baseline noise from the piezo signal before its being applied to a microphone channel of an existing PSG machine.

摘要翻译： 用于将热解/压电传感器连接到多导航测井机的适配器包括差分输入放大器，其被耦合以从PVDF膜换能器接收原始换能器信号，以在拒绝共模噪声的同时提供必要的增益。 滤波产生的放大信号以将pyro信号与压电信号分开，压电信号进一步施加到半波整流器级，其功能是在施加到现有PSG的麦克风通道之前从压电信号中去除基线噪声 机。

公开(公告)号：US06699204B1

公开(公告)日：2004-03-02

申请号：US09937424

申请日：2002-03-05

申请人： Georges Kehyayan ,  Ivan Kehayoff ,  Gérard Lenoir ,  Christian Avedissian ,  Bruno Roux

发明人： Georges Kehyayan ,  Ivan Kehayoff ,  Gérard Lenoir ,  Christian Avedissian ,  Bruno Roux

IPC分类号： A61B508

CPC分类号： A61B7/003

摘要： The invention concerns a device for analysing medical sounds, in particular respiratory sounds, comprising an input receiving a sound signal sampled in intensity levels each associated with a selected time, and storage means (2, 4, 5) comprising a processing module for evaluating, in cooperation with computing means (3), a set of transformed intensity levels, each associated with a predetermined sound frequency. It further comprises an output (26) connected to the storage means (2) for delivering each transformed intensity level in correspondence with an associated frequency, and means for representing (6, 90, 91) intensity levels transformed on the basis of frequencies, to obtain a spectral representation of the auscultation sound. The invention is characterised in that the processing module is further capable of evaluating a set of transformed intensity levels for each selected time, and the storage means (2) store each intensity level transformed on the basis of an associated frequency, and of a selected time, thereby providing a three-dimensional representation in time and in frequencies of the auscultation sound.

摘要翻译： 本发明涉及一种用于分析医疗声音，特别是呼吸声音的装置，包括接收以每个与所选择的时间相关联的强度级别采样的声音信号的输入端，以及包括处理模块的存储装置（2,4,5） 与计算装置（3）协作，一组变换的强度级别，每一个与预定的声音频率相关联。 它还包括连接到存储装置（2）的输出（26），用于传送与相关频率相对应的每个变换的强度电平;以及用于表示（6,90,91）基于频率变换的强度电平的装置， 获得听诊声音的频谱表示。 本发明的特征在于，处理模块还能够针对每个选定的时间评估一组变换的强度级别，并且存储装置（2）存储基于相关联的频率和选定时间变换的每个强度级别 从而在听诊声音的时间和频率上提供三维表示。

公开(公告)号：US06699203B2

公开(公告)日：2004-03-02

申请号：US10172271

申请日：2002-06-14

申请人： Eric W. Starr ,  Bernard Pennock ,  Mouhyieldin Kandis

发明人： Eric W. Starr ,  Bernard Pennock ,  Mouhyieldin Kandis

IPC分类号： A61B508

CPC分类号： A61B5/029 ,  A61B5/0833

摘要： A method and apparatus for use in determining the cardiac output. The method includes measuring a first parameter indicative of a patient's oxygen uptake and a second parameter indicative of the patient's fractional arterial oxygen concentration. The method also includes inducing a change in the patient's arterial oxygen concentration while taking these measurements to monitor the effects of the change in the patient's arterial oxygen concentration. The cardiac output is determined from the data collected regarding the effects of the change in the patient's arterial oxygen concentration.

摘要翻译： 一种用于确定心输出量的方法和装置。 该方法包括测量指示患者氧吸收的第一参数和指示患者分数动脉氧浓度的第二参数。 该方法还包括诱导患者动脉氧浓度的变化，同时进行这些测量以监测患者动脉氧浓度变化的影响。 从收集的关于患者动脉氧浓度变化的影响的数据中确定心输出量。

公开(公告)号：US06699202B1

公开(公告)日：2004-03-02

申请号：US09705654

申请日：2000-11-03

申请人： Rudolf Gambert ,  Peter Schubert ,  Kerstin Wex

发明人： Rudolf Gambert ,  Peter Schubert ,  Kerstin Wex

IPC分类号： A61B508

CPC分类号： A61B5/0833 ,  G06F19/00

摘要： A new method and a device are disclosed to determine physiologic parameters of a subject by analyzing it's breathing gas with an electrochemical sensor. The measured components of the breathing gas allow for many conclusions about the condition of the subjects's pulmonary system. It is therefore an objective of this invention to determine physiologic parameters from measuring the partial pressure of oxygen in the mainstream of the breathing gas. According to the invention the measurement can be performed non invasive and allows for conclusions about the respiratory and metabolic system of a subject. The invention makes a continuous measurement of the oxygen partial pressure possible, that almost shows no time delay. The invention allows for instance the determination of parameters like the oxygen concentration in the breathing gas, the oxygen consumption of the subject, the heart frequency, the respiratory quotient, the compliance of the pulmonary tract and other physiologic parameters.

摘要翻译： 公开了一种新的方法和装置，通过用电化学传感器分析其呼吸气体来确定受试者的生理参数。 呼吸气体的测量组分允许关于受试者的肺部系统的状况的许多结论。 因此，本发明的目的是通过测量呼吸气体主流中的氧分压来确定生理参数。 根据本发明，可以非侵入性地进行测量，并且允许关于受试者的呼吸和代谢系统的结论。 本发明可以连续测量氧气分压，几乎不显示时间延迟。 本发明允许例如确定呼吸气体中的氧气浓度，受试者的氧气消耗，心脏频率，呼吸商，肺动脉的顺应性和其他生理参数等参数。

公开(公告)号：US06669649B2

公开(公告)日：2003-12-30

申请号：US10142247

申请日：2002-05-09

申请人： Rocky Kahn

发明人： Rocky Kahn

IPC分类号： A61B508

CPC分类号： A61B5/0806 ,  A61H9/0021 ,  A61H2201/0103 ,  A61H2201/1654

摘要： A device for monitoring the breath of a user includes a tub containing a liquid for at least partially immersing the user in the liquid and a weight sensor positioned to sense weight information of the user while the user is at least partially immersed in the liquid. A controller is operably connected to the weight sensor to receive the weight information and is adapted to dynamically determine at least one of a respiratory phase of the user and a respiratory amplitude of the user using changes in the weight information over a period of time resulting from buoyancy changes of the user. The respiratory phase and/or the respiratory amplitude can be utilized to detect volitional breath commands, to detect pain thresholds of the user, to provide breath synchronized manipulations to the user, and to provide breath synchronized coaching signals to the user.

摘要翻译： 用于监测使用者的呼吸的装置包括容纳用于至少部分地将使用者浸入液体中的液体的桶，以及定位成在用户至少部分地浸入液体中时感测使用者的重量信息的重量传感器。 控制器可操作地连接到所述权重传感器以接收所述权重信息，并且适于使用所述权重信息中的至少一个来动态地确定所述用户的呼吸阶段和所述用户的呼吸振幅， 用户的浮力变化。 可以利用呼吸相位和/或呼吸振幅来检测呼吸指令，检测用户的疼痛阈值，向使用者提供呼吸同步操作，并向用户提供呼吸同步的辅导信号。

公开(公告)号：US06663574B2

公开(公告)日：2003-12-16

申请号：US10043000

申请日：2002-01-09

申请人： Joseph Dee Faram ,  Philip E. Fish

发明人： Joseph Dee Faram ,  Philip E. Fish

IPC分类号： A61B508

CPC分类号： A61M16/12 ,  A61B5/03 ,  A61B5/085 ,  A61M16/0006 ,  A61M16/021 ,  A61M16/04 ,  A61M16/0452 ,  A61M16/0459 ,  A61M16/08 ,  A61M16/0833 ,  A61M16/085 ,  A61M16/0858 ,  A61M16/206 ,  A61M16/208 ,  A61M2016/0021 ,  A61M2016/0027 ,  A61M2016/0039 ,  A61M2205/3569 ,  A61M2205/3576

摘要： A monitor-patient connector used with a lung inflection point monitor for measuring critical opening pressure, over distention pressure, and critical closing of lungs. The monitored-patient connector apparatus is used in conjunction with a lung inflection point monitor, and may be connected to a ventilator breathing circuit. The connector includes a proximal opening for connecting to a patient; a distal end that may be connected to the ventilator breathing circuit, a gas injection port for connecting the connector to a lung inflection point monitor; an isolation valve to prevent gas from entering and escaping during a lung inflection point maneuver; and an exhalation valve for regulating the evacuation of gas from the patient.

公开(公告)号：US06659960B2

公开(公告)日：2003-12-09

申请号：US10126298

申请日：2002-04-19

申请人： Frederik J. Derksen ,  Jennifer A. Brown

发明人： Frederik J. Derksen ,  Jennifer A. Brown

IPC分类号： A61B508

CPC分类号： A61B7/003

摘要： A portable recording unit (10) for recording the upper airway respiratory sounds of an exercising horse to determine whether the horse suffers from an upper airway obstruction condition. The portable recording unit (10) comprises horse restraining apparatus (200) wherein microphone (12) is mounted on support (14), which is secured to nose-band (202) of horse restraining apparatus (200), and recorder (16). When horse restraining apparatus (200) is mounted onto head (102) of horse (100), microphone (12) is positioned forward to and between nostrils (108) of horse (100). Recorder (16) is fastened to neck (104) of horse (100) or is located at a remote location. Portable recording unit (10) allows recording of the upper airway respiratory sounds made by the exercising horse (100).