公开(公告)号：US20240245733A1

公开(公告)日：2024-07-25

申请号：US18435722

申请日：2024-02-07

申请人： The Regents of the University of California ,  U.S. Govenment Represented by the Department of Veterans Affairs

发明人： Casey Ward ,  Qizhi TANG ,  Peter STOCK ,  Gaetano FALEO ,  Gopika NAIR ,  Matthias HEBROK ,  Wenhan CHANG ,  Thuy VO ,  Jeffrey A. BLUESTONE ,  Elenora DE KLERK

IPC分类号： A61K35/55 ,  A61K9/00 ,  A61K35/39 ,  A61P3/10 ,  C12N5/071

CPC分类号： A61K35/55 ,  A61K9/0019 ,  A61K9/0024 ,  A61K35/39 ,  A61P3/10 ,  C12N5/0617 ,  C12N5/0676 ,  A61K2300/00 ,  C12N2506/02 ,  C12N2506/078

摘要： Provided herein, inter alia, are methods and compositions for treating diabetes mellitus comprising co-transplantation of an insulin-producing cell and a cell derived from a parathyroid gland (PTG), a CD34+ cell derived from a parathyroid gland, a CD34+ cell derived from a stem cell, or other progenitor cell-derived CD34+ cell.

公开(公告)号：US11951136B2

公开(公告)日：2024-04-09

申请号：US16772078

申请日：2018-12-12

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  U.S. GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS

发明人： Casey Ward ,  Qizhi Tang ,  Peter Stock ,  Gaetano Faleo ,  Gopika Nair ,  Matthias Hebrok ,  Wenhan Chang ,  Thuy Vo ,  Jeffrey A. Bluestone ,  Eleonora De Klerk

IPC分类号： A61P3/10 ,  A61K9/00 ,  A61K35/39 ,  A61K35/55 ,  C12N5/071

CPC分类号： A61K35/55 ,  A61K9/0019 ,  A61K9/0024 ,  A61K35/39 ,  A61P3/10 ,  C12N5/0617 ,  C12N5/0676 ,  A61K2300/00 ,  C12N2506/02 ,  C12N2506/078

摘要： Provided herein, inter alia, are methods and compositions for treating diabetes mellitus comprising co-transplantation of an insulin-producing cell and a cell derived from a parathyroid gland (PTG), a CD34+ cell derived from a parathyroid gland, a CD34+ cell derived from a stem cell, or other progenitor cell-derived CD34+ cell.