-
1.发明公开公开(公告)号：US20230194473A1
公开(公告)日：2023-06-22
申请号：US17927137
申请日：2021-05-27
IPC分类号： G01N27/622 , H01J49/16 , H01J49/06 , H01J49/04
CPC分类号： G01N27/622 , H01J49/061 , H01J49/168 , H01J49/0422
摘要： A method of operating an ion mobility spectrometer comprises the following steps: drawing a sample of gaseous fluid into a reaction region of the ion mobility spectrometer; providing a first pulse of a pulsed ionisation source to ionise the sample of gaseous fluid, thereby to obtain first sample ions; after a first gate delay following the first trigger opening an ion shutter to permit a portion of the first sample ions to leave the reaction region; providing a second pulse of the pulsed ionisation source to further ionise the sample of gaseous fluid, thereby to obtain second sample ions; after a second gate delay following the first trigger opening the ion shutter to permit a portion of the second sample ions to leave the reaction region, wherein the second gate delay is different from the first gate delay.
-
公开(公告)号：US11150228B2
公开(公告)日：2021-10-19
申请号：US16806273
申请日：2020-03-02
发明人： Alastair Clark , Bruce Grant , Matthew Easton , Frederic Fournier
摘要： A detector comprising an analytical apparatus for detecting a substance of interest, and a detector inlet. The detector inlet comprises a flow passage for carrying a flow of fluid, the flow passage comprising a sampling volume, and a sampling inlet adapted to collect samples of the fluid from the sampling volume as the fluid flows past the sampling inlet, and to provide the samples to the analytical apparatus, wherein the how of fluid carries particulates. The detector inlet also comprises a flow director arranged to vary a spatial distribution of the particulates carried by the fluid to increase a relative proportion of the particulates carried past the sampling inlet along the flow passage without entering the sampling volume.
-
公开(公告)号：US20210249242A1
公开(公告)日：2021-08-12
申请号：US17241773
申请日：2021-04-27
发明人： David Sharp , Alastair Clark , William Munro , Paul Amold , John Fitzgerald , David Cutmore , Rod Wilson
IPC分类号： H01J49/00 , G01N27/62 , G01N27/622 , G01N27/626
摘要： A portable ion mobility spectrometry apparatus (1) for detecting an aerosol and a method for using the apparatus. The apparatus comprises an ion mobility spectrometer (3); a portable power source (5) carried by the apparatus for providing power to the apparatus (1); an inlet (7) for collecting a flow of air to be tested by the spectrometer (3); a heater (4) configured to heat the air to be tested to vapourise an aerosol carried by the air and a controller (2) configured to control the spectrometer (3) to obtain samples from the heated air, wherein the controller is configured to increase a heat output from the heater (4) for a selected time period before obtaining samples from the heated air.
-
公开(公告)号：US10557823B2
公开(公告)日：2020-02-11
申请号：US15518574
申请日：2015-10-14
发明人： Alastair Clark , Jonathan Atkinson
摘要： An ion filter for a mass spectrometer, the apparatus comprising an ion modifier; an ion selector configured to select a subset of a sample of ions based on their mobility in a gas; and a controller configured to operate the ion modifier in a first mode to modify the ions selected by the ion selector to provide daughter ions, and configured to operate the ion modifier in a second mode to output the ions selected by the ion selector; wherein the ion filter is adapted for providing output ions from the ion modifier to an intake of a mass spectrometer.
-
公开(公告)号：US10018593B2
公开(公告)日：2018-07-10
申请号：US15515842
申请日：2015-09-29
发明人： William Angus Munro
CPC分类号： G01N27/622 , H01J49/0027 , H01J49/061
摘要： An ion mobility spectrometer (100) comprising a first ion source (102-1, 108-1) for providing positive ions to be analyzed, an electric field applier arranged to provide an electric field configured to move the positive ions in a first direction towards a first ion detector (106-1, 110-1) adapted for detecting the positive ions, and a second ion source (102-2, 108-2) for providing negative ions to be analyzed, wherein the electric field applier is arranged to move the negative ions in a direction opposite to the first direction, towards the first ion source (102-1, 108-1) and towards a second ion detector (106-1, 110-1) adapted for detecting the negative ions.
-
公开(公告)号：US09541524B2
公开(公告)日：2017-01-10
申请号：US14370838
申请日：2013-02-15
IPC分类号： G01N27/62
CPC分类号： G01N27/622
摘要： Synchronized ion modification systems and techniques are described. An ion modifier can be used to modify a portion of ions that enter a drift chamber via a gate that controls entry of the ions to the drift chamber. A controller that is communicatively coupled to the ion modifier is configured to control the ion modifier to select a portion of the ion to be modified. In embodiments, the controller selects the portion based on a detector's previous response to other ions that are formed from a sample from which the ions were formed. The other ions, for example, correspond to ions that are associated with a peak in previous operation of a spectrometer.
摘要翻译： 描述了同步离子修饰系统和技术。 离子修饰剂可用于通过控制离子进入漂移室的栅极来修饰进入漂移室的一部分离子。 通信地耦合到离子改性剂的控制器被配置为控制离子修饰剂以选择待修饰的离子的一部分。 在实施例中，控制器基于检测器对从形成离子的样品形成的其它离子的先前响应来选择该部分。 例如，其它离子对应于在光谱仪的先前操作中与峰值相关联的离子。
-
公开(公告)号：US09463468B2
公开(公告)日：2016-10-11
申请号：US14400407
申请日：2013-05-15
发明人： Alex Paul Hiley
CPC分类号： H03K3/012 , B03B5/08 , G01N27/622 , H01F19/04 , H01F27/255 , H01F27/28 , H03H7/38
摘要： RF generators including active devices driving series resonant circuits are described. The series resonant circuits include a self-resonant dual inductor. The RF generators can be used to drive capacitive loads.
摘要翻译： 描述了包括驱动串联谐振电路的有源器件的RF发生器。 串联谐振电路包括自谐振双电感器。 RF发生器可用于驱动容性负载。
-
公开(公告)号：US09324546B2
公开(公告)日：2016-04-26
申请号：US14400639
申请日：2013-05-31
CPC分类号： H01J49/025 , G01N27/622 , H01J49/022
摘要： Spectrometers including integrated capacitive detectors are described. An integrated capacitive detector integrates ion current from the collector (220) into a changing voltage. The detector includes a collector configured to receive ions in the spectrometer, a dielectric (228), and a plate (232) arranged in an overlapping configuration with collector on an opposite side of the dielectric. The detector also includes an amplifier (226).
摘要翻译： 描述了包含集成电容式检测器的光谱仪。 集成电容检测器将来自集电极（220）的离子电流集成到变化的电压中。 检测器包括被配置为在光谱仪中接收离子的集电器，电介质（228）和以与电介质的相对侧上的集电器重叠配置的板（232）。 检测器还包括放大器（226）。
-
9.发明授权Detection apparatus accompanying preconcentrated pulsed analyte via an aperture 有权通过孔径与预浓缩的脉冲分析物相关的检测装置公开(公告)号：US08734722B2
公开(公告)日：2014-05-27
申请号：US12521542
申请日：2007-12-10
申请人： Stephen John Taylor
发明人： Stephen John Taylor
CPC分类号： G01N33/0004 , G01N27/622 , Y10T436/24 , Y10T436/25875
摘要： IMS apparatus has a preconcentrator outside its inlet aperture. Analyte vapor is adsorbed during a first phase when substantially no gas is admitted to the reaction region. The preconcentrator is then energized to desorb the analyte molecules and create a volume of desorbed molecules outside the IMS housing. Next, a pressure pulser is energized momentarily to drop pressure in the housing and draw in a small sip of the analyte molecules from the desorbed volume through the aperture. This is repeated until the concentration of analyte molecules in the desorbed volume is too low for accurate analysis, following which the apparatus enters another adsorption phase.
摘要翻译： IMS设备在其入口孔之外具有预浓缩器。 当基本上没有气体进入反应区域时，分析物蒸汽在第一阶段被吸附。 然后将预浓缩器通电以解吸分析物分子，并在IMS壳体外部产生一定量的解吸分子。 接下来，压力脉冲发生器被瞬间通电以降低壳体中的压力，并且通过孔从吸收的体积中吸取小口径的分析物分子。 重复这一操作，直到解吸体积中分析物分子的浓度太低以进行精确分析，随后装置进入另一吸附阶段。
-
公开(公告)号：US08648296B2
公开(公告)日：2014-02-11
申请号：US13850123
申请日：2013-03-25
发明人： William Angus Munro
CPC分类号： H01J49/10 , G01N27/622 , H01J49/26 , H01J49/40 , H01J49/403
摘要： An ion mobility spectrometer has several electrodes spaced along its ion source region. Voltages are applied to the electrodes to produce a voltage gradient along the length of the ion source region. By varying the voltage gradient, the residence time of ions in the ion source region can be selectively varied. Typically, the spectrometer is arranged to reduce the residence time in response to a decrease in the amplitude of an ion peak detected at the far end of the drift region.
摘要翻译： 离子迁移谱仪具有沿其离子源区域间隔开的多个电极。 电压被施加到电极以沿着离子源区域的长度产生电压梯度。 通过改变电压梯度，可以选择性地改变离子在离子源区域中的停留时间。 通常，光谱仪布置成响应于在漂移区域的远端检测到的离子峰值的振幅的减小而减少停留时间。
-
-
-
-
-
-
-
-
-
搜索结果
98 条记录 (耗时 0.023 秒)
