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公开(公告)号：US10537474B2
公开(公告)日：2020-01-21
申请号：US15601756
申请日：2017-05-22
申请人： IVANTIS, INC.
摘要： An ocular implant for treating glaucoma is provided, which may include any number of features. More particularly, the present invention relates to implants that facilitate the transfer of fluid from within one area of the eye to another area of the eye. One feature of the implant is that it includes a proximal inlet portion and a distal inlet portion adapted to be inserted into the anterior chamber of the eye, and an intermediate portion adapted to be inserted into Schlemm's canal. Another feature of the implant is that it can be biased to assume a predetermined shape to aid in placement within the eye.
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公开(公告)号：US10390993B1
公开(公告)日：2019-08-27
申请号：US16404530
申请日：2019-05-06
申请人： IVANTIS, INC.
发明人： Michael S. Berlin
摘要： An apparatus having an inserter device with a shaft disposed in an interior space and an intraocular implant adapted to self-retain to an inner wall of Schlemm's canal. The intraocular implant has a proximal portion sized and shaped to reside within an anterior chamber of the eye, the proximal portion having a proximal opening; a distal portion sized and shaped to reside within Schlemm's canal of the eye, the distal portion having a distal opening, and a passageway extending in a straight line from the proximal opening to the distal opening to conduct fluid from the anterior chamber to Schlemm's canal. The shaft of the inserter device is adapted to advance the intraocular implant out of the interior space and through an inner wall of Schlemm's canal.
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公开(公告)号：US10335314B2
公开(公告)日：2019-07-02
申请号：US16196260
申请日：2018-11-20
申请人： IVANTIS, INC.
发明人： Michael S. Berlin
摘要： An apparatus having an inserter device with a shaft disposed in an interior space and an intraocular implant adapted to self-retain to an inner wall of Schlemm's canal. The intraocular implant has a proximal portion sized and shaped to reside within an anterior chamber of the eye, the proximal portion having a proximal opening; a distal portion sized and shaped to reside within Schlemm's canal of the eye, the distal portion having a distal opening, and a passageway extending in a straight line from the proximal opening to the distal opening to conduct fluid from the anterior chamber to Schlemm's canal. The shaft of the inserter device is adapted to advance the intraocular implant out of the interior space and through an inner wall of Schlemm's canal.
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公开(公告)号：US09931243B2
公开(公告)日：2018-04-03
申请号：US14592703
申请日：2015-01-08
申请人： IVANTIS, INC.
发明人： John Wardle , Andrew T. Schieber
CPC分类号： A61F9/0026 , A61B17/3421 , A61B17/3468 , A61B2017/3454 , A61F9/0017 , A61F9/00781 , A61F2220/0033
摘要： A method of deploying an ocular implant into Schlemm's canal of an eye. The method includes the steps of inserting a distal end of a cannula through a cornea of the eye and into an anterior chamber of the eye, the cannula having a distal opening extending from the distal end and through a side wall; placing the distal opening of the cannula into fluid communication with Schlemm's canal; advancing the ocular implant distally through the cannula with a delivery tool engaged with the ocular implant, a proximal portion of the ocular implant engaging the delivery tool proximal to a distal portion of the delivery tool; and disengaging the ocular implant and the delivery tool when the proximal portion of the ocular implant reaches the cannula distal opening. The invention also includes a system for practicing the method.
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公开(公告)号：US08551166B2
公开(公告)日：2013-10-08
申请号：US13681365
申请日：2012-11-19
IPC分类号： A61F2/16
CPC分类号： A61F9/00781 , A61M25/0068 , A61M25/01 , A61M31/00 , A61M2025/0004
摘要： A method of deploying an ocular implant into Schlemm's canal of a human eye including the following steps: inserting a distal tip of a delivery tool within an anterior chamber of the eye through trabecular meshwork of the eye into Schlemm's canal of the eye; and advancing an ocular implant through a curved portion and a distal opening of the delivery tool to place a body portion of the ocular implant in Schlemm's canal and an inlet portion of the ocular implant in the anterior chamber.
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公开(公告)号：US08425449B2
公开(公告)日：2013-04-23
申请号：US12833863
申请日：2010-07-09
申请人： John Wardle , Andrew T. Schieber , Kenneth M. Galt
发明人： John Wardle , Andrew T. Schieber , Kenneth M. Galt
IPC分类号： A61M5/00
CPC分类号： A61F9/0017 , A61F9/0026 , A61F9/00781
摘要： An ocular implant is provided. In some embodiments, the ocular implant includes a body that is curved about a longitudinal central axis and a distal body portion that defines a longitudinal channel including a channel opening. The implant is sized and configured such that the ocular implant assumes an orientation in which the channel opening is adjacent a major side of Schlemm's canal when the ocular implant is disposed in Schlemm's canal. Methods for delivering ocular implants into Schlemm's canal are also provided. Some methods include covering openings in the ocular implant, advancing the implant into Schlemm's canal while at least some of the openings are covered, and uncovering the openings while the distal portion of the implant is disposed in Schlemm's canal.
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公开(公告)号：US08282592B2
公开(公告)日：2012-10-09
申请号：US12775266
申请日：2010-05-06
CPC分类号： A61F9/00781 , A61F9/0017 , A61F2009/00891 , A61M27/002 , A61M2210/0612
摘要： An ocular implant adapted to reside at least partially in a portion of Schlemm's canal of an eye. In some embodiments the implant has a body extending in a curved volume whose longitudinal axis forms an arc of a circle, and a plurality of open areas and strut areas formed in the body, the open areas extending over more than 50% of a surface defining the curved volume, the strut areas surrounding the open areas, the body having a diameter of between 0.005 inches and 0.04 inches. The invention also provides a method of treating glaucoma including the steps of supporting tissue forming Schlemm's canal in an eye with an implant extending at least partially in the canal along an axial length within the canal; and contacting with the implant less than 50% of the tissue forming the canal along the axial length.
摘要翻译： 适于至少部分地居住在眼睛的施莱姆氏管的一部分中的眼部植入物。 在一些实施例中，植入物具有在弯曲体积中延伸的主体，其纵向轴线形成圆弧，以及形成在主体中的多个开放区域和支柱区域，所述开放区域延伸超过表面的50％以上 弯曲的体积，围绕开放区域的支柱区域，主体具有在0.005英寸和0.04英寸之间的直径。 本发明还提供一种治疗青光眼的方法，包括以下步骤：在眼睛中支撑组织形成施莱姆氏管，其中植入物至少部分地沿着管内的轴向长度延伸至管内; 并且沿着轴向长度与植入物接触形成管的少于50％的组织。
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公开(公告)号：US11504275B2
公开(公告)日：2022-11-22
申请号：US16689508
申请日：2019-11-20
申请人： IVANTIS, INC.
摘要： An ocular implant for treating glaucoma is provided, which may include any number of features. More particularly, the present invention relates to implants that facilitate the transfer of fluid from within one area of the eye to another area of the eye. One feature of the implant is that it includes a proximal inlet portion and a distal inlet portion adapted to be inserted into the anterior chamber of the eye, and an intermediate portion adapted to be inserted into Schlemm's canal. Another feature of the implant is that it can be biased to assume a predetermined shape to aid in placement within the eye.
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公开(公告)号：US20220096271A1
公开(公告)日：2022-03-31
申请号：US17548212
申请日：2021-12-10
申请人： IVANTIS, INC.
发明人： John WARDLE , Andrew T. SCHIEBER
摘要： An ocular implant delivery system is provided with a number of features. In some embodiments, the delivery system comprises a rotation mechanism configured to rotate and orient a cannula of the system, and an advancement mechanism configured to advance and retract an ocular implant through the delivery system and into an eye of a patient. In some embodiments, the cannula is sized and configured to be inserted into Schlemm's canal of the eye. The ocular implant is configured to maintain its orientation within the delivery system as the cannula is rotated. In some embodiments, the ocular implant automatically disengages the delivery system when it is advanced beyond a distal tip of the delivery system. Methods of implanting an ocular implant are also provided.
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公开(公告)号：US10687978B2
公开(公告)日：2020-06-23
申请号：US16525267
申请日：2019-07-29
申请人： IVANTIS, INC.
发明人： Michael S. Berlin
摘要： An apparatus having an inserter device with a shaft disposed in an interior space and an intraocular implant adapted to self-retain to an inner wall of Schlemm's canal. The intraocular implant has a proximal portion sized and shaped to reside within an anterior chamber of the eye, the proximal portion having a proximal opening; a distal portion sized and shaped to reside within Schlemm's canal of the eye, the distal portion having a distal opening, and a passageway extending in a straight line from the proximal opening to the distal opening to conduct fluid from the anterior chamber to Schlemm's canal. The shaft of the inserter device is adapted to advance the intraocular implant out of the interior space and through an inner wall of Schlemm's canal.
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