-
公开(公告)号：US20250041389A1
公开(公告)日：2025-02-06
申请号：US18789450
申请日：2024-07-30
Inventor： Janet Funk
Abstract: Methods for enhancing the therapeutic effects of phenols comprising the oral coadministration or sequential oral administration of a phenol and glucuronidase, and compositions for enhancing the therapeutic effects of phenols.
-
公开(公告)号：US12196943B2
公开(公告)日：2025-01-14
申请号：US17421748
申请日：2020-01-09
Inventor： James B. Breckinridge
Abstract: An optical system comprising a segmented optical element comprising a plurality of segments disposed adjacent each other to define a pupil, wherein one or more of the plurality of segments comprises a pair of curved edges, wherein the segmented optical element is arranged such that a curved gap is defined between adjacent segments.
-
公开(公告)号：US12189141B2
公开(公告)日：2025-01-07
申请号：US17256044
申请日：2019-06-28
Inventor： Thomas D. Milster , Daniel Apai , Lee C. Johnson
Abstract: A multi-order diffractive Fresnel lens (MOD-DFL) that is suitable for use in a space telescope for studying transiting earth-like planets of distant stars is provided. The MOD-DFL may comprise a MOD-DFL array comprising a plurality of MOD-DFL segments that are secured to a mounting surface of a deployment device, such as a balloon, for example, in a preselected arrangement to form the MOD-DFL. An array telescope may be formed of an array of deployment devices, such as an array of balloons, for example, each having a MOD-DFL secured to a mounting surface of the respective deployment device, an optics system disposed inside of the respective deployment device, and a camera disposed inside of the respective deployment device. Each MOD-DFL comprises a plurality of MOD-DFL segments arranged in a preselected arrangement to form the respective MOD-DFL.
-
公开(公告)号：US12180300B2
公开(公告)日：2024-12-31
申请号：US17277828
申请日：2019-09-20
Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA , UNIVERSITY OF UTAH RESEARCH FOUNDATION
Inventor： Youngwook Won , David A. Bull , Daniel Yongwon Lee
Abstract: Surface-engineered immune cells, such as natural killer cells, grafted with targeting moiety-drug complexes. The present invention combines chemotherapy and immunotherapy by engineering the immune cells to target specific tumor cells through antigen recognition and deliver potent chemotherapeutic agents, thereby destroying the tumor cells. The surface-engineered immune cells may be prepared using a one-step method. The present invention also provides kits for preparing the surface-engineered immune cells.
-
公开(公告)号：US20240418921A1
公开(公告)日：2024-12-19
申请号：US18687757
申请日：2022-08-30
Inventor： Sawyer Miller , Linan Jiang , Stanley Pau
Abstract: Methods, devices and systems are described to eliminate or reduce unwanted polarization aberrations associated with interference filters. An example method for producing a polarization aberration compensator for a thin film interference filter includes obtaining a set of Mueller matrix values based on polarization measurements of the thin film interference filter over a spectral range, and generating a metric based on a difference between a compensated Mueller matrix and an identity matrix over the spectral range. The compensated matrix represents a cumulative Mueller matrix for a combination of the thin film interference filter and the polarization aberration compensator. A configuration of the polarization aberration compensator is determined based on evaluating the metric that eliminates or reduces the difference between the compensated Mueller matrix and the identity matrix over the spectral range. Configuration parameters, including thicknesses of birefringent layers, fast-axis angles and the number of birefringent layers in the compensator are obtained.
-
Patent Agency Ranking
公开(公告)号：US20240408244A1
公开(公告)日：2024-12-12
申请号：US18702693
申请日：2022-10-21
Inventor： Rui Chang , Roberta Diaz Brinton , Rima Kaddurah-Daouk
Abstract: Provided herein are compositions and methods for diagnosing, prognosing, and treating neurodegenerative diseases in a male and female subject at risk of or diagnosed with a neurodegenerative disease. In particular, provided herein are customized metabolite analyses for characterizing and treating neurodegenerative diseases in specific subject groups from a sample from said subject.
-
公开(公告)号：US20240407770A1
公开(公告)日：2024-12-12
申请号：US18186146
申请日：2023-03-17
Applicant: Arizona Board of Regents on Behalf of the University of Arizona , DATA DRIVEN DIAGNOSTIC SCIENCES, INC., DBA D3SCIENCES
Inventor： Michael C. Larson , Charles T. Hennemeyer
Abstract: A biopsy system for harvesting larger volumes of tissue as compared to standard core biopsy needles. The system has a needle with a lumen, an aperture disposed at the distal end of the needle and connected to the lumen, and a cutting mechanism adapted to cut tissue. When the needle is rotated after it is inserted into a target tissue, the cutting mechanism cuts from the tissue and directs the cut tissue portions into the lumen. Multi-bioimpedance measurements are used to guide a needle and direct the application of electricity for cauterizing tissue.
-
公开(公告)号：US12164181B2
公开(公告)日：2024-12-10
申请号：US18213147
申请日：2023-06-22
Inventor： James T. Schwiegerling
Abstract: A diffractive multifocal lens is disclosed, comprising an optical element having at least one diffractive surface, the surface profile comprising a plurality of annular concentric zones. The optical thickness of the surface profile changes monotonically with radius within each zone, while a distinct step in optical thickness at the junction between adjacent zones defines a step height. The step heights for respective zones may differ from one zone to another periodically so as to tailor diffraction order efficiencies of the optical element. In one example of a trifocal lens, step heights alternate between two values, the even-numbered step heights being lower than the odd-numbered step heights. By plotting a topographical representation of the diffraction efficiencies resulting from such a surface profile, step heights may be optimized to direct a desired level of light power into the diffraction orders corresponding to near, intermediate, and distance vision, thereby optimizing the performance of the multifocal lens.
-
公开(公告)号：US20240402301A1
公开(公告)日：2024-12-05
申请号：US18693196
申请日：2022-09-22
Inventor： Wenhua He , Salkat Guha
IPC: G01S7/48 , G01S7/481 , H04B10/112 , H04B10/70
Abstract: An optical beam is provided from a transmitter aperture to a receiver aperture that receives the optical beam after displacement by a path shifting component. Received initial displacement information characterizing at least one of: an initial estimate of the displacement, or an indication that the displacement is below a predetermined threshold. Received input beams each have a different spatial mode, from a set of mutually orthogonal spatial modes that include: a lowest order spatial mode, a highest order spatial mode, and one or more intermediate order spatial modes. A relative amount of each of the input beams to be included in the optical beam is determined based at least in part on: corresponding diffraction loss estimates for each of the input beams, and the initial displacement information. One of the input beams that has a largest relative amount in the optical beam is one of the intermediate order spatial modes.
-
公开(公告)号：US20240395170A1
公开(公告)日：2024-11-28
申请号：US18674202
申请日：2024-05-24
Inventor： Diego Celdran-Bonafonte
IPC: G09B23/34
Abstract: Surgical training devices, kits, and associated methods are disclosed. The surgical training devices include a body shaped to correspond to an animal. The surgical training devices also include an insert for removable insertion into an opening in the body. The insert can be to be covered by a cover, which can be removably attached to the insert. An entirety or majority of the body, the insert, and the cover can be formed of materials sourced from sources other than the animal.
-
-
-
-
-
-
-
-
-
Search Results
1489
records
(took 0.131 seconds)
