专利检索 ap:("ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD.") AND inv:"Quan Han" 第 1 页

1.

发明授权
Combination product containing limonoid compound and biguanide compound 有权

公开(公告)号：US11679097B2

公开(公告)日：2023-06-20

申请号：US16637018

申请日：2018-07-13

申请人： ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD.

发明人： Dong Li , Quan Han , Liu Hu , Lian Xue

IPC分类号： A61K31/366 , A61K31/155 , A61K31/585 , A61K31/7048 , C07J73/00 , A61P3/04 , A61P3/10 , A61P3/00

CPC分类号： A61K31/366 , A61K31/155 , A61K31/585 , A61K31/7048 , A61P3/04 , A61P3/10

摘要： The present invention relates to a combination product comprising a limonoid compound (or a pharmaceutically acceptable derivative, ester, stereoisomer, salt or prodrug thereof), and a biguanide compound (e.g., metformin, metformin hydrochloride, buformin, and phenformin). The present invention further relates to a use of the combination product for prevention and/or treatment of a disease associated with diabetes, for lipid-lowering and weight-loss, and the like.