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公开(公告)号：US09353145B2
公开(公告)日：2016-05-31
申请号：US14350456
申请日：2012-10-09
申请人： ZACH SYSTEM
发明人： Yvon Derrien , Patricia Poirier , Massimiliano Forcato , Tony Pintus , Livius Cotarca , Sebastien Meunier , Laurence Graindorge
CPC分类号： C07J43/003 , C07J1/0059 , C07J31/003 , C07J31/006
摘要： The present invention relates to a process for the preparation of 17-substituted steroids and, more particularly, to an improved method of synthesizing abiraterone or derivatives thereof in high yield and purity by means of a key 3-formate intermediate.
摘要翻译： 本发明涉及一种制备17-取代的类固醇的方法，更具体地说，涉及通过关键的3-甲酸中间体以高产率和纯度合成阿非特酮或其衍生物的改进方法。
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公开(公告)号：US09920089B2
公开(公告)日：2018-03-20
申请号：US14785110
申请日：2014-04-11
申请人： ZACH SYSTEM
CPC分类号： C07J43/003 , C07J43/006
摘要： The present invention relates to a process for the preparation of 17-substituted steroids and, more particularly, to an improved method of preparing micro size abiraterone or derivatives thereof in high yield and purity by means of a spherical agglomeration process.
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公开(公告)号：US20140256932A1
公开(公告)日：2014-09-11
申请号：US14350456
申请日：2012-10-09
申请人： ZACH SYSTEM
发明人： Yvon Derrien , Patricia Poirier , Massimiliano Forcato , Tony Pintus , Livius Cotarca , Sebastien Meunier , Laurence Graindorge
CPC分类号： C07J43/003 , C07J1/0059 , C07J31/003 , C07J31/006
摘要： The present invention relates to a process for the preparation of 17-substituted steroids and, more particularly, to an improved method of synthesizing abiraterone or derivatives thereof in high yield and purity by means of a key 3-formate intermediate.
摘要翻译： 本发明涉及一种制备17-取代的类固醇的方法，更具体地说，涉及通过关键的3-甲酸中间体以高产率和纯度合成阿非特酮或其衍生物的改进方法。
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