公开(公告)号：US07215736B1

公开(公告)日：2007-05-08

申请号：US11072635

申请日：2005-03-04

Applicant: Yuxin Wang ,  Wenbing Yun ,  David Dean Scott

Inventor： Yuxin Wang ,  Wenbing Yun ,  David Dean Scott

IPC: G01N23/00

CPC classification number: G01N23/046 ,  A61B6/508 ,  G01N2223/419

Abstract: A projection x-ray imaging system that possibly utilizes a laboratory-based micro-focused x-ray source is disclosed. Techniques for optimizing the system for high quality, three dimensional image formation with tomographic imaging with the potential for high resolution and high throughput are described. It also concerns ways to optimize the system design to obtain improved image quality.

Abstract translation: 公开了可能利用基于实验室的微焦点x射线源的投影X射线成像系统。 描述了用于利用具有高分辨率和高吞吐量的潜力的断层成像优化用于高质量三维图像形成的系统的技术。 它还涉及到优化系统设计以获得改进的图像质量的方法。

公开(公告)号：US20080205734A1

公开(公告)日：2008-08-28

申请号：US12029790

申请日：2008-02-12

Applicant: Yuxin Wang ,  Wenbing Yun ,  David Dean Scott

Inventor： Yuxin Wang ,  Wenbing Yun ,  David Dean Scott

IPC: G06K9/00 ,  G01N23/00

CPC classification number: G01N23/046 ,  A61B6/508 ,  G01N2223/419

Abstract: A projection x-ray imaging system that possibly utilizes a laboratory-based micro-focused x-ray source is disclosed. Techniques for optimizing the system for high quality, three dimensional image formation with tomographic imaging with the potential for high resolution and high throughput are described. It also concerns ways to optimize the system design to obtain improved image quality.

Abstract translation: 公开了可能利用基于实验室的微焦点x射线源的投影X射线成像系统。 描述了用于利用具有高分辨率和高吞吐量的潜力的断层成像优化用于高质量三维图像形成的系统的技术。 它还涉及到优化系统设计以获得改进的图像质量的方法。

公开(公告)号：US07130375B1

公开(公告)日：2006-10-31

申请号：US11035749

申请日：2005-01-14

Applicant: Wenbing Yun ,  David Dean Scott ,  David R. Trapp ,  Frederick William Duewer ,  Yuxin Wang

Inventor： Wenbing Yun ,  David Dean Scott ,  David R. Trapp ,  Frederick William Duewer ,  Yuxin Wang

IPC: G01N23/20

CPC classification number: G01N23/04 ,  A61B6/508 ,  G01N2223/505 ,  G01N2223/6113

Abstract: A projection-based x-ray imaging system combines projection magnification and optical magnification in order to ease constraints on source spot size, while improving imaging system footprint and efficiency. The system enables tomographic imaging of the sample especially in a proximity mode where the same is held in close proximity to the scintillator. In this case, a sample holder is provided that can rotate the sample. Further, a z-axis motion stage is also provided that is used to control distance between the sample and the scintillator.

Abstract translation: 基于投影的X射线成像系统结合了投影放大倍数和光学放大倍率，以便减轻源光斑尺寸的限制，同时提高成像系统的覆盖面和效率。 该系统使得样品的层析成像特别是在接近模式下，其中相邻的模式保持在闪烁体附近。 在这种情况下，提供可以旋转样品的样品架。 此外，还提供了用于控制样品和闪烁体之间的距离的z轴运动级。

公开(公告)号：US07400704B1

公开(公告)日：2008-07-15

申请号：US11537806

申请日：2006-10-02

Applicant: Wenbing Yun ,  David Dean Scott ,  David R. Trapp ,  Frederick William Duewer ,  Yuxin Wang

Inventor： Wenbing Yun ,  David Dean Scott ,  David R. Trapp ,  Frederick William Duewer ,  Yuxin Wang

IPC: G01N23/20 ,  A61B6/08 ,  H05G1/00

CPC classification number: G01N23/04 ,  A61B6/508 ,  G01N2223/505 ,  G01N2223/6113

Abstract: A projection-based x-ray imaging system combines projection magnification and optical magnification in order to ease constraints on source spot size, while improving imaging system footprint and efficiency. The system enables tomographic imaging of the sample especially in a proximity mode where the same is held in close proximity to the scintillator. In this case, a sample holder is provided that can rotate the sample. Further, a z-axis motion stage is also provided that is used to control distance between the sample and the scintillator.

Abstract translation: 基于投影的X射线成像系统结合了投影放大倍数和光学放大倍率，以便减轻源光斑尺寸的限制，同时提高成像系统的覆盖面和效率。 该系统使得样品的层析成像特别是在接近模式下，其中相邻的模式保持在闪烁体附近。 在这种情况下，提供可以旋转样品的样品架。 此外，还提供了用于控制样品和闪烁体之间的距离的z轴运动级。

公开(公告)号：US07388942B2

公开(公告)日：2008-06-17

申请号：US11682503

申请日：2007-03-06

Applicant: Yuxin Wang ,  Wenbing Yun ,  David Dean Scott

Inventor： Yuxin Wang ,  Wenbing Yun ,  David Dean Scott

IPC: A61B6/03

CPC classification number: G01N23/046 ,  A61B6/508 ,  G01N2223/419

Abstract: A projection x-ray imaging system that possibly utilizes a laboratory-based micro-focused x-ray source is disclosed. Techniques for optimizing the system for high quality, three dimensional image formation with tomographic imaging with the potential for high resolution and high throughput are described. It also concerns ways to optimize the system design to obtain improved image quality.

Abstract translation: 公开了可能利用基于实验室的微焦点x射线源的投影X射线成像系统。 描述了用于利用具有高分辨率和高吞吐量的潜力的断层成像优化用于高质量三维图像形成的系统的技术。 它还涉及到优化系统设计以获得改进的图像质量的方法。

公开(公告)号：US07561662B2

公开(公告)日：2009-07-14

申请号：US12029790

申请日：2008-02-12

Applicant: Yuxin Wang ,  Wenbing Yun ,  David Dean Scott

Inventor： Yuxin Wang ,  Wenbing Yun ,  David Dean Scott

IPC: G01N23/00

CPC classification number: G01N23/046 ,  A61B6/508 ,  G01N2223/419

Abstract: A projection x-ray imaging system that possibly utilizes a laboratory-based micro-focused x-ray source is disclosed. Techniques for optimizing the system for high quality, three dimensional image formation with tomographic imaging with the potential for high resolution and high throughput are described. It also concerns ways to optimize the system design to obtain improved image quality.

Abstract translation: 公开了可能利用基于实验室的微焦点x射线源的投影X射线成像系统。 描述了用于利用具有高分辨率和高吞吐量的潜力的断层成像优化用于高质量三维图像形成的系统的技术。 它还涉及到优化系统设计以获得改进的图像质量的方法。

公开(公告)号：US07286640B2

公开(公告)日：2007-10-23

申请号：US10990198

申请日：2004-11-16

Applicant: Wenbing Yun ,  Yuxin Wang ,  David Dean Scott

Inventor： Wenbing Yun ,  Yuxin Wang ,  David Dean Scott

IPC: H05G1/64 ,  G01T1/20

CPC classification number: G01T1/202 ,  G01T1/2018 ,  G21K2207/005

Abstract: A digital dual-band detector functions as an imaging platform capable of extracting hard and soft tissue images, for example. The detector has a first detector system comprising a first scintillator for converting x-rays from a sample to an first optical signal, and a first detector for detecting the first optical signal in combination with a second detector system comprising a second scintillator for converting x-rays from the sample and passing through the first scintillator to a second optical signal, and a second detector for detecting the second optical signal. The detector can facilitate the implementation and deployment of recent developments and can permit low cost practical deployment in clinical applications as well as biomedical research applications where significant improvement in spatial resolution and image contrast is required.

Abstract translation: 例如，数字双频带检测器用作能够提取硬和软组织图像的成像平台。 检测器具有第一检测器系统，该第一检测器系统包括用于将来自样品的x射线转换成第一光信号的第一闪烁器，以及用于与第二检测器系统一起检测第一光信号的第一检测器，该第二检测器系统包括用于将x- 来自样品的光并通过第一闪烁体到第二光信号;以及第二检测器，用于检测第二光信号。 检测器可以促进近期发展的实施和部署，并且可以允许临床应用中的低成本实际部署以及需要显着改善空间分辨率和图像对比度的生物医学研究应用。

公开(公告)号：US20080165924A1

公开(公告)日：2008-07-10

申请号：US11619705

申请日：2007-01-04

Applicant: Yuxin Wang ,  Wenbing Yun

Inventor： Yuxin Wang ,  Wenbing Yun

IPC: G01N23/00

CPC classification number: G01N23/04

Abstract: An imaging technology for fuel cells is based on x-ray microscopy. A metrology system images the electrochemical interaction areas of solid-oxide fuel cells (SOFC) in-situ. This system takes advantage of both the penetrating power and elemental absorption contrast of hard x-ray radiation to image the internal interaction areas in a SOFC. The technology can further take advantage of the strong dependence of the x-ray absorption on material type and energy to distinguish the four major material types: cathode, electrolyte, air, and low-Z contaminants such as sulfur.

Abstract translation: 燃料电池的成像技术基于x射线显微镜。 测量系统原位形成固体氧化物燃料电池（SOFC）的电化学相互作用区域。 该系统利用硬X射线辐射的穿透力和元素吸收对比度来对SOFC中的内部相互作用区域进行成像。 该技术可以进一步利用x射线吸收对材料类型和能量的强烈依赖性，以区分四种主要材料类型：阴极，电解质，空气和低Z污染物如硫。

公开(公告)号：US07365909B2

公开(公告)日：2008-04-29

申请号：US10688187

申请日：2003-10-17

Applicant: Wenbing Yun ,  Yuxin Wang ,  Michael Feser ,  Alan Lyon

Inventor： Wenbing Yun ,  Yuxin Wang ,  Michael Feser ,  Alan Lyon

IPC: G02B27/44

CPC classification number: G02B27/4211 ,  G02B3/08 ,  G02B27/4272 ,  G03F7/0005 ,  Y10S438/975

Abstract: Methods for fabricating refractive element(s) and aligning the elements in a compound optic, typically to a zone plate element. The techniques are used for fabricating micro refractive, such as Fresnel, optics and compound optics including two or more optical elements for short wavelength radiation. One application is the fabrication of the Achromatic Fresnel Optic (AFO). Techniques for fabricating the refractive element generally include: 1) ultra-high precision mechanical machining, e.g,. diamond turning; 2) lithographic techniques including gray-scale lithography and multi-step lithographic processes; 3) high-energy beam machining, such as electron-beam, focused ion beam, laser, and plasma-beam machining; and 4) photo-induced chemical etching techniques. Also addressed are methods of aligning the two optical elements during fabrication and methods of maintaining the alignment during subsequent operation.

Abstract translation: 用于制造折射元件并将复合光学元件中的元件对准的方法，通常与区域板元件对准。 这些技术用于制造微折射，例如菲涅尔，光学和复合光学器件，包括用于短波长辐射的两个或更多个光学元件。 一种应用是制造消色差菲涅耳光（AFO）。 用于制造折射元件的技术通常包括：1）超高精度机械加工，例如 钻石车削 2）光刻技术，包括灰阶光刻和多步光刻工艺; 3）高能束加工，如电子束，聚焦离子束，激光和等离子束加工; 和4）光诱导化学蚀刻技术。 还涉及在制造期间对准两个光学元件的方法以及在随后的操作期间维持对准的方法。

公开(公告)号：US07297959B2

公开(公告)日：2007-11-20

申请号：US11278839

申请日：2006-04-06

Applicant: Wenbing Yun ,  Yuxin Wang ,  David R. Trapp

Inventor： Wenbing Yun ,  Yuxin Wang ,  David R. Trapp

IPC: G01T1/20

CPC classification number: G01T1/2002 ,  G01T1/20

Abstract: A scintillated CCD detector system for imaging x rays uses x-rays having a photon energy in the range of 1 to 20 keV. The detector differs from existing systems in that it provides extremely high resolution of better than a micrometer, and high detection quantum efficiency of up to 95%. The design of this detector also allows it to function as an energy filter to remove high-energy x-rays. This detector is useful in a wide range of applications including x-ray imaging, spectroscopy, and diffraction. The scintillator optical system has scintillator material with a lens system for collecting the light that is generated in the scintillator material. A substrate is used for spacing the scintillator material from the lens system.

Abstract translation: 用于对x射线进行成像的闪烁CCD检测器系统使用具有在1至20keV范围内的光子能量的X射线。 检测器与现有系统不同之处在于它提供比千分尺更高的分辨率，高达95％的高检测量子效率。 该检测器的设计也可以用作能量过滤器，以去除高能X射线。 该检测器可用于广泛的应用，包括X射线成像，光谱和衍射。 闪烁体光学系统具有闪烁体材料，其具有用于收集闪烁体材料中产生的光的透镜系统。 衬底用于将闪烁体材料与透镜系统间隔开。