公开(公告)号：US20240350607A1

公开(公告)日：2024-10-24

申请号：US18687463

申请日：2022-08-30

Applicant: Vir Biotechnology, Inc.

Inventor： Ann M. Arvin ,  Julia Di Iulio ,  Janet L. Douglas ,  Emily Marshall ,  Leah B. Soriaga ,  Herbert W. Virgin

IPC: A61K39/04 ,  A61K39/00 ,  C07K14/35 ,  C12N5/0783 ,  C12N15/86

CPC classification number: A61K39/04 ,  A61K39/4611 ,  C07K14/35 ,  C12N5/0636 ,  C12N15/86 ,  A61K2039/5256 ,  C07K2319/42 ,  C12N2510/00 ,  C12N2710/16143

Abstract: The disclosure relates to tuberculosis antigens and vectors for delivering the antigens. The disclosure also relates to immunogenic compositions comprising the same, and their uses.

公开(公告)号：US20230282305A1

公开(公告)日：2023-09-07

申请号：US18019905

申请日：2021-08-06

Applicant: Vir Biotechnology, Inc.

Inventor： Amalio Telenti ,  Julia Di Iulio

IPC: G16B20/00 ,  G16B40/20 ,  G16H50/70 ,  G16H50/20

CPC classification number: G16B20/00 ,  G16B40/20 ,  G16H50/70 ,  G16H50/20

Abstract: Universal signatures represent generalizable features that are informative for generating predictions for different disease activities across different diseases. More specifically, one or more universal signatures are learned from data pertaining to a first disease indication and then applied to generate predictions for a one or more additional disease indications. The implementation of one or more universal signatures is useful for generating predictions for disease indications, such as disease indications involving rare or novel diseases, where it may be infeasible to develop a model due to insufficient training data.