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公开(公告)号：US20170204133A1
公开(公告)日：2017-07-20
申请号：US15313139
申请日：2015-06-17
发明人： Alicia REGUEIRO-REN , Animesh GOSWAMI , Zhiwei GUO , Thomas P. TULLY , Jacob SWIDORSKI , Zheng LIU , Nicholas A. MEANWELL
CPC分类号： C07J63/008 , C07J71/001 , C07J71/0026
摘要： Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, betulinic acid derivaties that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II and III: These compounds are useful for the treatment of HIV and AIDS.
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公开(公告)号：US20170334946A1
公开(公告)日：2017-11-23
申请号：US15524298
申请日：2015-11-12
IPC分类号： C07J63/00
CPC分类号： C07J63/008
摘要： Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I and II: These compounds are useful for the treatment of HIV and AIDS.
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