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公开(公告)号：US20190031709A1
公开(公告)日：2019-01-31
申请号：US16071925
申请日：2017-02-02
发明人： Jie CHEN , Yan CHEN , Ira B. DICKER , Richard A. HARTZ , Nicholas A. MEANWELL , Beata NOWICKA-SANS , Alicia REGUEIRO-REN , Sing-Yuen SIT , Ny SIN , Jacob SWIDORSKI , Brian Lee VENABLES
CPC分类号： C07J53/002 , A61P31/18 , C07J63/008 , C12N9/506 , C12N2740/16222
摘要： Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formula I: These compounds are useful for the treatment of HIV and AIDS.
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公开(公告)号：US20190135857A1
公开(公告)日：2019-05-09
申请号：US16306083
申请日：2017-06-28
摘要： Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, triterpenoid compounds that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formula I: These compounds are useful for the treatment of HIV and AIDS.
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