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![Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide](/abs-image/US/2022/04/05/US11291662B2/abs.jpg.150x150.jpg)
公开(公告)号：US11291662B2
公开(公告)日：2022-04-05
申请号：US16704713
申请日：2019-12-05
发明人： Patricia Hurter , William Rowe , Christopher R. Young , Adriana Costache , Patrick R. Connelly , Mariusz Krawiec , Yuchuan Gong , Yushi Feng , Martin Trudeau
IPC分类号： A61K31/47 , C07D215/56
摘要： The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
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![Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide](/abs-image/US/2017/06/06/US09670163B2/abs.jpg.150x150.jpg)
公开(公告)号：US09670163B2
公开(公告)日：2017-06-06
申请号：US14852892
申请日：2015-09-14
发明人： Patricia Hurter , William Rowe , Christopher R. Young , Adriana Costache , Patrick R. Connelly , Mariusz Krawiec , Yuchuan Gong , Yushi Feng , Martin Trudeau
IPC分类号： C07D215/56 , A61K31/47
CPC分类号： A61K31/47 , A61K2300/00 , C07B2200/13 , C07D215/56 , Y10T428/2982
摘要： The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
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![SOLID FORMS OF N-[2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXAMIDE](/abs-image/US/2023/08/24/US20230263794A1/abs.jpg.150x150.jpg)
3.发明公开公开(公告)号：US20230263794A1
公开(公告)日：2023-08-24
申请号：US17953412
申请日：2022-09-27
发明人： Patricia Hurter , William Rowe , Christopher R. Young , Adriana Costache , Patrick R. Connelly , Mariusz Krawiec , Yuchuan Gong , Yushi Feng , Martin Trudeau
IPC分类号： A61K31/47 , C07D215/56
CPC分类号： A61K31/47 , C07D215/56 , A61K2300/00 , C07B2200/13 , Y10T428/2982
摘要： The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
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![SOLID FORMS OF N-[2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXAMIDE](/abs-image/US/2019/03/07/US20190070162A1/abs.jpg.150x150.jpg)
4.发明申请公开(公告)号：US20190070162A1
公开(公告)日：2019-03-07
申请号：US15900147
申请日：2018-02-20
发明人： Patricia Hurter , William Rowe , Christopher R. Young , Adriana Costache , Patrick R. Connelly , Mariusz Krawiec , Yuchuan Gong , Yushi Feng , Martin Trudeau
IPC分类号： A61K31/47 , C07D215/56
CPC分类号： A61K31/47 , A61K2300/00 , C07B2200/13 , C07D215/56 , Y10T428/2982
摘要： The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
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![Solid Forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide](/abs-image/US/2013/11/28/US20130317060A1/abs.jpg.150x150.jpg)
5.发明申请Solid Forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide 有权固体形式的N- [2,4-双（1,1-二甲基乙基）-5-羟基苯基] -1,4-二氢-4-氧代喹啉-3-甲酰胺公开(公告)号：US20130317060A1
公开(公告)日：2013-11-28
申请号：US13785692
申请日：2013-03-05
发明人： Patricia Hurter , William Rowe , Christopher R. Young , Adriana Costache , Patrick R. Connelly , Mariusz Krawiec , Yuchuan Gong , Yushi Feng , Martin Trudeau
IPC分类号： C07D215/56
CPC分类号： A61K31/47 , A61K2300/00 , C07B2200/13 , C07D215/56 , Y10T428/2982
摘要： The present invention relates to solid state forms of N—[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
摘要翻译： 本发明涉及N- [2,4-双（1,1-二甲基乙基）-5-羟基苯基] -1,4-二氢-4-氧代喹啉-3-甲酰胺（化合物1）的固体形式，药物组合物 及其方法。
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![Solid forms of N[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide](/abs-image/US/2018/04/03/US09931334B2/abs.jpg.150x150.jpg)
公开(公告)号：US09931334B2
公开(公告)日：2018-04-03
申请号：US15584324
申请日：2017-05-02
发明人： Patricia Hurter , William Rowe , Christopher R. Young , Adriana Costache , Patrick R. Connelly , Mariusz Krawiec , Yuchuan Gong , Yushi Feng , Martin Trudeau
IPC分类号： A61K31/47
CPC分类号： A61K31/47 , A61K2300/00 , C07B2200/13 , C07D215/56 , Y10T428/2982
摘要： The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
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![Solid Forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide](/abs-image/US/2014/08/28/US20140242172A1/abs.jpg.150x150.jpg)
7.发明申请Solid Forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide 有权固体形式的N- [2,4-双（1,1-二甲基乙基）-5-羟基苯基] -1,4-二氢-4-氧代喹啉-3-甲酰胺公开(公告)号：US20140242172A1
公开(公告)日：2014-08-28
申请号：US14272692
申请日：2014-05-08
发明人： Patricia Hurter , William Rowe , Christopher R. Young , Adriana Costache , Patrick R. Connelly , Mariusz Krawiec , Yuchuan Gong , Yushi Feng , Martin Trudeau
IPC分类号： C07D215/56 , A61K31/47
CPC分类号： A61K31/47 , A61K2300/00 , C07B2200/13 , C07D215/56 , Y10T428/2982
摘要： The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
摘要翻译： 本发明涉及N- [2,4-双（1,1-二甲基乙基）-5-羟基苯基] -1,4-二氢-4-氧代喹啉-3-甲酰胺（化合物1）的固体形式，药物组合物 及其方法。
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![SOLID FORMS OF N-[2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXAMIDE](/abs-image/US/2021/08/19/US20210251978A9/abs.jpg.150x150.jpg)
公开(公告)号：US20210251978A9
公开(公告)日：2021-08-19
申请号：US16704713
申请日：2019-12-05
发明人： Patricia Hurter , William Rowe , Christopher R. Young , Adriana Costache , Patrick R. Connelly , Mariusz Krawiec , Yuchuan Gong , Yushi Feng , Martin Trudeau
IPC分类号： A61K31/47 , C07D215/56
摘要： The present invention relates to solid state forms of N-[2,4-bis(1,1-diethylethyl)-5-hydroxyphenyl]-1,4-dihydro-1-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
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公开(公告)号：US20210023070A1
公开(公告)日：2021-01-28
申请号：US16842480
申请日：2020-04-07
发明人： William Rowe , Patricia Hurter , Christopher Young , Kirk Dinehart , Marinus Jacobus Verwijs , Kirk Overhoff , Peter D.J. Grootenhuis , Martyn Botfield , Alfredo Grossi
摘要： The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.
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![SOLID FORMS OF N-[2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXAMIDE](/abs-image/US/2017/08/17/US20170231970A1/abs.jpg.150x150.jpg)
10.发明申请公开(公告)号：US20170231970A1
公开(公告)日：2017-08-17
申请号：US15584324
申请日：2017-05-02
发明人： Patricia Hurter , William Rowe , Christopher R. Young , Adriana Costache , Patrick R. Connelly , Mariusz Krawiec , Yuchuan Gong , Yushi Feng , Martin Trudeau
IPC分类号： A61K31/47
CPC分类号： A61K31/47 , A61K2300/00 , C07B2200/13 , C07D215/56 , Y10T428/2982
摘要： The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
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